Physical Sciences and Mathematics Commons^™

Design And Control Of A Peristaltic Pump To Simulate Left Atrial Pressure In A Conductive Silicone Model, Jeremy Collins

Mechanical Engineering Undergraduate Honors Theses

According to the CDC, atrial fibrillation is responsible for more than 454,000 hospitalizations and approximately 158,000 deaths per year. A common treatment for atrial fibrillation is catheter ablation, a process in which a long flexible tube is guided through the femoral artery and to the source of arrhythmia in the heart, where it measures the electrical potential at various locations and converts problematic heart tissue to scar tissue via ablation. This paper details the design and control of a low-cost ($400) peristaltic pump system using repetitive control to replicate blood pressure in the left atrium in a conductive silicone model …

Deep Learning Methods For Image Restoration And Reconstruction, Zahra Anvari

Computer Science and Engineering Dissertations

The problem of image reconstruction and restoration refers to recovering the clean images from corrupted ones. Corruption or degradation can occur due to atmospheric conditions such as rain, fog, mist, snow, dust, and air pollution or technical drawbacks of imaging devices such as motion blurriness, compression noise, low-resolution, etc. Image reconstruction algorithms aim at reducing these artifacts and degradation and generate clear images. Scenes captured under bad weather conditions such as rain, fog, mist, and haze suffer from visibility issues thus introduce obstacles for computer vision applications, e.g. object detection, recognition, tracking, and segmentation. In this dissertation, we focus on …

Kopos: A Framework To Study And Detect Physical And Cognitive Fatigue Concurrently, Varun Ajay Kanal

Computer Science and Engineering Dissertations

Fatigue is one of the most prevalent phenomena in human beings, and yet its detection is highly subjective and poorly understood. The phenomenon of fatigue has a huge impact on performance, the ability to execute tasks safely and correctly, and the ability to retain or secure a job. Fatigue can be classified into two types: physical and cognitive fatigue. Physical fatigue may occur due to excessive physical exertion, while cognitive fatigue may occur due to excessive mental exertion. Historically, these two types of fatigue have been studied independently. However, in the real world, although these often occur at the same …

Extend The Sensing Boundary Of Mobile Systems: Security And New Applications, Wenqiang Jin

Computer Science and Engineering Dissertations

The exploding growth of mobile devices like smartphones and wearables has envisioned various applications, which are developed to collect a wide spectrum of data using on-board device sensors and process them to serve peoples' life in all kinds of scenarios. Noticing the sensing capabilities of current mobile device are limited to its on-board sensors' default functionalities. We study the mechanism designs that extend the mobile device's sensing capabilities to perform new sensing tasks other than its defaults. In this thesis, we investigate the mobile systems' security issues and develop new applications by exploring the device's sensing capabilities. Our contributions are …

Hardness Test Of Grb 950830 As A Gravitationally Lensed Echo, Oindabi Mukherjee, Robert J. Nemiroff

Michigan Tech Publications

Cumulative hardness comparisons are a simple but statistically powerful test for the presence of gravitational lensing in gamma-ray bursts (GRBs). Since gravitational lensing does not change photon energies, all source images should have the same spectra—and hence hardness. Applied to the recent claim that the two pulses in GRB 950830 are lensed images of the same pulse, the measured flux ratio between the two main pulses should be the same at all energies. After summing up all the counts in both of GRB 950830's two pulses in all four BATSE energy bands, it was found that in energy channel 3, …

The Effect Of The Apolipoprotein A1 (Apoa1): The Stability And Folding In Potassium Chloride Environment, Alexandra Paladian

Honors Theses

Healthy levels of potassium chloride (KCl) can significantly affect the workings of the cholesterol level of the human body and how they pertain to an individual person. The search for a better salt additive for the human diet can provide a better option for people who experience high cholesterol levels and heart disease. The study focuses on the experimental design of the Molecular Dynamic (MD) simulation of the Apolipoprotein A1 (APOA1) in the potassium ion solution environment to determine the stability and folding of the protein. The study also compares its data to the previous experimental design of chloride ions …

Security Fatigue And Its Effects On Perceived Password Strength Among University Students, Chase Carroll

Honors Theses

This study was performed with the goal of observing the effect, if any, that security fatigue has on students’ perceived strength of passwords. In doing so, it was hoped to find some correlation between the two that would help in establishing a measurable effect of the phenomenon in students. This could potentially aid organizational decision-makers, such as security policy writers and system admins, to make more informed decisions about implementing security measures. To achieve the goal of observing this fatigue and attempting to measure it, a survey was distributed to numerous students on the University of Tennessee at Chattanooga campus. …

Optimal Analytical Methods For High Accuracy Cardiac Disease Classification And Treatment Based On Ecg Data, Jianwei Zheng

Computational and Data Sciences (PhD) Dissertations

This work constitutes six projects. In the first project, a newly inaugurated research database for 12-lead electrocardiogram signals was created under the auspices of Chapman University and Shaoxing People's Hospital (Shaoxing Hospital Zhejiang University School of Medicine). This database aims to enable the scientific community in conducting new studies on arrhythmia and other cardiovascular conditions. In the second project, we created a new 12-lead ECG database under the auspices of Chapman University and Ningbo First Hospital of Zhejiang University that aims to provide high quality data enabling detection of the distinctions between idiopathic ventricular arrhythmia from right ventricular outflow tract …

Assessing The Re-Identification Risk In Ecg Datasets And An Application Of Privacy Preserving Techniques In Ecg Analysis, Arin Ghazarian

Computational and Data Sciences (PhD) Dissertations

In this work, first we investigate the use of ECG signal as a biometric in human identification systems using deep learning models. We train convolutional neural network models on ECG samples from approximately 81k patients. Our models achieved an over-all accuracy of 95.69%. Further, we assess the accuracy of our ECG identification model for distinct groups of patients with particular heart conditions and combinations of such conditions. For example, we observed that the identification accuracy was the highest (99.7%) for patients with both ST changes and supraventricular tachycardia. On the other hand, we also found that the identification rate was …

Electrodeposition Of Hydrogen Molybdenum Tungsten Bronze Films And Electrochemical Reduction Of Carbon Dioxide., Mohammad Bajunaid

Electronic Theses and Dissertations

The foremost aim for performing this study was to focus on the electrodeposition of mixed hydrogen molybdenum tungsten bronze films, which have the potential for e^– transfer interactions carrying out the reduction of carbon dioxide. A yellow peroxymolybdic tungstate solution was prepared and used for the electrodeposition of hydrogen molybdenum tungsten bronze films on conductive carbon paper. Electrodeposition was carried out at -2.0 V from 20 - 120 minutes to determine the effect of deposition time on film thickness and CO₂ reduction. These films were characterized by X-ray photoelectron spectroscopy. The deposited films served as a working electrode …

Constructions & Optimization In Classical Real Analysis Theorems, Abderrahim Elallam

Electronic Theses and Dissertations

This thesis takes a closer look at three fundamental Classical Theorems in Real Analysis. First, for the Bolzano Weierstrass Theorem, we will be interested in constructing a convergent subsequence from a non-convergent bounded sequence. Such a subsequence is guaranteed to exist, but it is often not obvious what it is, e.g., if an = sin n. Next, the H¨older Inequality gives an upper bound, in terms of p ∈ [1,∞], for the the integral of the product of two functions. We will find the value of p that gives the best (smallest) upper-bound, focusing on the Beta and Gamma integrals. …

Investigating The Role Of Charge Separation In Triplet State Formation In Zinc Dipyrrin Photosensitizers, Irene Y. Dzaye

Electronic Theses and Dissertations

About 85% of the world’s energy is derived from non-renewable sources—coal, petroleum, and natural gas. Solar photocatalysis is one way to potentially generate cheap renewable fuels by harnessing energy from the sun using a photosensitizer and converting it into chemical energy. The efficiency of a photosensitizer depends on its capacity to form a prolonged triplet excited state. Zinc dipyrrin complexes have the potential to be efficient sensitizers for reductive photochemistry, but their ability to form long-lived triplet excited states still needs extensive research. The overall aim of this research is to probe the role charge separation plays in the formation …

Morphology And Paleoecology Of Nimravides Galiani (Felidae) And Barbourofelis Loveorum (Barbourofelidae) From The Late Miocene Of Florida, Christianne Ormsby

Electronic Theses and Dissertations

Saber-toothed remains have been found worldwide throughout the Cenozoic, until the end of the Pleistocene. One site from Alachua County, Florida preserves a diverse Miocene fauna, including the machairodontine Nimravides galiani (Felidae) and the saber-toothed Barbourofelis loveorum (Barbourofelidae). Both taxa roamed what would become the Love Bone Bed site during the Late Miocene (Late Clarendonian NALMA), ~ 9.5 Mya. Previous descriptions focused on crania; yet the large sample of postcrania remained undescribed. Hence, this project includes a detailed postcranial description of both taxa. Results show that N. galiani resembles extant felids, whereas B. loveorum resembles Smilodon fatalis, as well …

Performance Comparison Of Multiple Imputation Methods For Quantitative Variables For Small And Large Data With Differing Variability, Vincent Onyame

Electronic Theses and Dissertations

Missing data continues to be one of the main problems in data analysis as it reduces sample representativeness and consequently, causes biased estimates. Multiple imputation methods have been established as an effective method of handling missing data. In this study, we examined multiple imputation methods for quantitative variables on twelve data sets with varied sizes and variability that were pseudo generated from an original data. The multiple imputation methods examined are the predictive mean matching, Bayesian linear regression and linear regression, non-Bayesian in the MICE (Multiple Imputation Chain Equation) package in the statistical software, R. The parameter estimates generated from …

Non-Gaussian Measurements Of Coherent States Of Light For Metrology And Communication, Matthew Dimario

Physics & Astronomy ETDs

Conventional measurement technology is unable to extract the most amount of information possible from coherent states of light. Non-Gaussian measurements which can count individual photons can surpass the sensitivity limits of ideal conventional strategies, and approach the ultimate limits achievable given by quantum mechanics. This thesis presents investigations and demonstrations of these unconventional measurements, which utilize coherent operations and single photon counting. This thesis shows that non-Gaussian measurements can outperform conventional strategies in estimation tasks as well as a variety of communication problems. This thesis also investigates novel approaches and algorithms for building robustness to static and dynamic noise which …

Machine Learning Approaches To Dribble Hand-Off Action Classification With Sportvu Nba Player Coordinate Data, Dembe Stephanos

Electronic Theses and Dissertations

Recently, strategies of National Basketball Association teams have evolved with the skillsets of players and the emergence of advanced analytics. One of the most effective actions in dynamic offensive strategies in basketball is the dribble hand-off (DHO). This thesis proposes an architecture for a classification pipeline for detecting DHOs in an accurate and automated manner. This pipeline consists of a combination of player tracking data and event labels, a rule set to identify candidate actions, manually reviewing game recordings to label the candidates, and embedding player trajectories into hexbin cell paths before passing the completed training set to the classification …

Characterization Of The Differential Expressed Genes And Transcriptomic Pathway Analysis In The Liver Of Sub-Adult Red Drum (Sciaenops Ocellatus) Exposed To Deepwater Horizon Chemically Dispersed Oil, Tracy A. Sherwood, Maria L. Rodgers, Andrea M. Tarnecki, Dana L. Wetzel

Faculty Publications

The Deepwater Horizon blowout resulted in the second-largest quantity of chemical dispersants used as a countermeasure for an open water oil spill in the Gulf of Mexico. Of which, the efficacy of dispersant as a mitigation strategy and its toxic effects on aquatic fauna remains controversial. To enhance our understanding of potential sub-lethal effects of exposure to chemically dispersed-oil, sub-adult red drum (Sciaenops ocellatus) were continuously exposed to a Corexit 9500: DWH crude oil chemically enhanced water accommodated fraction (CEWAF) for 3-days and transcriptomic responses were assessed in the liver. Differential expressed gene (DEG) analysis demonstrated that 63 …

Proper Sum Graphs, Austin Nicholas Beard

MSU Graduate Theses

The Proper Sum Graph of a commutative ring with identity has the prime ideals as vertices, with two ideals adjacent if their sum is a proper ideal. This thesis expands upon the research of Dhorajia. We will cover the groundwork to understanding the basics of these graphs, and gradually narrow our efforts into the minimal prime ideals of the ring.

Cross Domain Iw Threats To Sof Maritime Missions: Implications For U.S. Sof, Gary C. Kessler, Diane M. Zorri

Publications

As cyber vulnerabilities proliferate with the expansion of connected devices, wherein security is often forsaken for ease of use, Special Operations Forces (SOF) cannot escape the obvious, massive risk that they are assuming by incorporating emerging technologies into their toolkits. This is especially true in the maritime sector where SOF operates nearshore in littoral zones. As SOF—in support to the U.S. Navy— increasingly operate in these contested maritime environments, they will gradually encounter more hostile actors looking to exploit digital vulnerabilities. As such, this monograph comes at a perfect time as the world becomes more interconnected but also more vulnerable.

Predicting Suboptimal Care In Insured Nebraskans With Known And Suspected Chronic Conditions., Avery Wallace

Capstone Experience

Health insurance companies have a goal of improving population health for their members (people who the company insures). As a health insurance company, [Company] has ample data on the health of its members that can be utilized to improve the health, and by extension lives of the people they insure. Although [Company] does not deliver care, they communicate with their members and physicians to identify ways to improve the health of the member. Of specific interest are members with known chronic conditions who are receiving suboptimal care, as well as members who have undiagnosed chronic conditions. Two chronic conditions were …

Biases And Blind-Spots In Genome-Wide Crispr-Cas9 Knockout Screens, Merve Dede

Dissertations & Theses (Open Access)

Adaptation of the bacterial CRISPR-Cas9 system to mammalian cells revolutionized the field of functional genomics, enabling genome-scale genetic perturbations to study essential genes, whose loss of function results in a severe fitness defect. There are two types of essential genes in a cell. Core essential genes are absolutely required for growth and proliferation in every cell type. On the other hand, context-dependent essential genes become essential in an environmental or genetic context. The concept of context-dependent gene essentiality is particularly important in cancer, since killing cancer cells selectively without harming surrounding healthy tissue remains a major challenge. The toxicity of …

Development Of Quantitative Ultrasound-Mediated Molecular Imaging Of The Tumor Microenvironment, Trevor Mitcham

Dissertations & Theses (Open Access)

While conventional diagnostic imaging modalities provide anatomical information to clinicians, these techniques are not sensitive to critical physiological processes. In order to properly classify cancer, it is necessary to investigate noninvasive methods which can provide insight into these processes, allowing clinicians to determine personalized therapeutic options. Therefore, molecular imaging is focused on visualization and characterization of biomarkers within the tumor microenvironment (TME), which can then be combined with the anatomical information provided from diagnostic imaging.

Two such biomarkers of interest are blood oxygen saturation (SO₂) and cell receptor expression. SO₂ is a measure of the fraction of …

Mixture Model Approaches To Integrative Analysis Of Multi-Omics Data And Spatially Correlated Genomic Data, Ziqiao Wang

Dissertations & Theses (Open Access)

Integrative genomic data analysis is a powerful tool to study the complex biological processes behind a disease. Statistical methods can model the interrelationships of the involved gene activities through jointly analyzing multiple types of genomic data from different platforms (vertical integration), or improve the power of a study through aggregating the same type of genomic data across studies (horizontal integration). In this dissertation, we propose statistical methods and strategies for integrative multi-omics data in association analysis of disease phenotypes, with an emphasis on cancer applications.

We develop a new strategy based on horizontal integration by leveraging publicly available datasets into …

Plasma Aerodynamics: Experimental Quantification Of The Lift Force Generated On An Airfoil Using Plasma Actuation To Estimate Power Requirements In Small Uav Applications, Getachew Ashenafi

UNLV Theses, Dissertations, Professional Papers, and Capstones

This research addressed the amount of electric power required to induce specific changes in lift force using a NACA 2127 airfoil with a chord length of ~28 mm, connected to a micro load cell, in a wind tunnel of 103 square centimeter cross-section. A DBD plasma actuator supplied by a ZVS driven high voltage pulsed DC circuit, operating at a frequency of 17.4 kHz, was utilized for voltages of up to 5000 V. Two configurations of electrode gapping were compared to determine the efficient use of power. The configuration with a gap of ~1 mm between the upstream and downstream …

Theranostic Nanoparticles Folic Acid-Carbon Dots-Drug(S) For Cancer, Godwin Kweku Babanyinah

Electronic Theses and Dissertations

This study aims to prepare theranostic nanoparticles (NPs) that are expected to increase cancer diagnostics and therapeutic efficacy. We prepared the NPs constituting carbon dots (CDs) as an imaging agent, folic acid as a targeting agent, doxorubicin (DOX), or gemcitabine (GEM) as chemotherapy agents. The NPs include noncovalent FA-CDs-DOX, covalent CDs-FA-DOX, and covalent FA-CDs-GEM. Through ultraviolet-visible spectroscopy, fluorescence spectroscopy, and Fourier transform-infrared spectroscopy, the fabrication of these NPs was confirmed. It was discovered that the high drug loading efficiency is the noncovalent series while the high drug loading capacity is the covalent series The in-vitro pH-dependent drug release data indicate …

Plprepare: A Grammar Checker For Challenging Cases, Jacob Hoyos

Electronic Theses and Dissertations

This study investigates one of the Polish language’s most arbitrary cases: the genitive masculine inanimate singular. It collects and ranks several guidelines to help language learners discern its proper usage and also introduces a framework to provide detailed feedback regarding arbitrary cases. The study tests this framework by implementing and evaluating a hybrid grammar checker called PLPrepare. PLPrepare performs similarly to other grammar checkers and is able to detect genitive case usages and provide feedback based on a number of error classifications.

Algebraic Structures And Variations: From Latin Squares To Lie Quasigroups, Erik Flinn

All NMU Master's Theses

In this Master's Thesis we give an overview of the algebraic structure of sets with a single binary operation. Specifically, we are interested in quasigroups and loops and their historical connection with Latin squares; considering them in both finite and continuous variations. We also consider various mappings between such algebraic objects and utilize matrix representations to give a negative conclusion to a question concerning isotopies in the case of quasigroups.

Visualizing Geometric Structures On Topological Surfaces, Andrea Clark

All NMU Master's Theses

We study an interplay between topology, geometry, and algebra. Topology is the study of properties unchanged by bending, stretching or twisting space. Geometry measures space through concepts such as length, area, and angles. In the study of two-dimensional surfaces one can go back and forth between picturing twists as either distortions of the geometric properties of the surface or as a wrinkling of the surface while leaving internal measures unchanged. The language of groups gives us a way to distinguish geometric structures. Understanding the mapping class group is an important and hard problem. This paper contributes to visualizing how the …

Proteomic Analysis Of Mycobacteriophage Crimd, William Moeller

Undergraduate Honors Theses

Bacteriophages represent a large portion of the biomatter on our planet, and many of them have yet to be fully characterized. Here we discuss the proteomic analysis of a particular Bacteriophage, Mycobacteriophage CrimD. This phage was discovered on the Campus of William & Mary and has had its genome characterized. We took the next logical step of proteomic analysis.

In our analyses we made use high pressure liquid chromatography paired with linear ion trap mass spectrometry to analyze the proteome of CrimD at specific time points after the infection of its host, Mycobacterium smegmatis. Additionally, we used nanospray ionization with …

Using Machine Learning To Track The Location Of The Shock Train In Hypersonic Engines, Alison Reynolds

Undergraduate Honors Theses

Proposed hypersonic vehicles would be able to travel at five to ten times the speed of sound, but there are still many problems that need to be solved to construct a functioning vehicle. One such problem involves shocks created in the engine isolator when the vehicle reaches high speeds. These shocks must be contained to the isolator to maximize performance and avoid potential failure. This project attempts to track the location of the leading shock given images of airflow from ground tests of engines using random forests and convolutional neural networks. When the models are trained and tested on data …