Physical Sciences and Mathematics Commons^™

Multispectral Deep Neural Network Fusion Method For Low-Light Object Detection, Keval Thaker, Sumanth Chennupati, Nathir Rawashdeh, Samir A. Rawashdeh

Michigan Tech Publications, Part 2

Despite significant strides in achieving vehicle autonomy, robust perception under low-light conditions still remains a persistent challenge. In this study, we investigate the potential of multispectral imaging, thereby leveraging deep learning models to enhance object detection performance in the context of nighttime driving. Features encoded from the red, green, and blue (RGB) visual spectrum and thermal infrared images are combined to implement a multispectral object detection model. This has proven to be more effective compared to using visual channels only, as thermal images provide complementary information when discriminating objects in low-illumination conditions. Additionally, there is a lack of studies on …

Symmetries And Integrable Systems, Sen-Yue Lou, Bao-Feng Feng

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Symmetry plays key roles in modern physics especially in the study of integrable systems because of the existence of infinitely many local and nonlocal generalized symmetries. In addition to the fundamental role to find exact group invariant solutions via Lie point symmetries, some important new developments on symmetries and conservation laws are reviewed. The recursion operator method is important to find infinitely many local and nonlocal symmetries of (1+1)-dimensional integrable systems. In this paper, it is pointed out that a recursion operator may be obtained from one key symmetry, say, a residual symmetry. For (2+1)-dimensional integrable systems, the master-symmetry approach …

Dice Are Blessed Or Cursed, Warren Campbell, Cameron Miller

SEAS Faculty Publications

Dice are cursed or blessed; that is, they roll low or high, but they are never fair. They cannot be manufactured with uniform density and geometric precision. This is particularly true of 20-sided dice or D20s. Faces are smaller than 6-sided dice, and manufacturing tolerances are similar. However, some dice are fairer than others. In our studies of plastic-mold dice about 1 in 4 test fair in 3000 rolls. We have used different statistical tests, including chi-square, modified Kolmogorov Smirnov, and double binomial tests. Of these, the method that consistently performed better is the chi-square goodness of fit test. The …

The Great Scrape: The Clash Between Scraping And Privacy, Daniel J. Solove, Woodrow Hartzog

Faculty Scholarship

Artificial intelligence (AI) systems depend on massive quantities of data, often gathered by “scraping” – the automated extraction of large amounts of data from the internet. A great deal of scraped data is about people. This personal data provides the grist for AI tools such as facial recognition, deep fakes, and generative AI. Although scraping enables web searching, archival, and meaningful scientific research, scraping for AI can also be objectionable or even harmful to individuals and society.

Organizations are scraping at an escalating pace and scale, even though many privacy laws are seemingly incongruous with the practice. In this Article, …

Outsourcing Voting To Ai: Can Chatgpt Advise Index Funds On Proxy Voting Decisions?, Chen Wang

Fordham Journal of Corporate & Financial Law

Released in November 2022, Chat Generative Pre-training Transformer (“ChatGPT”), has risen rapidly to prominence, and its versatile capabilities have already been shown in a variety of fields. Due to ChatGPT’s advanced features, such as extensive pre-training on diverse data, strong generalization ability, fine-tuning capabilities, and improved reasoning, the use of AI in the legal industry could experience a significant transformation. Since small passive funds with low-cost business models generally lack the financial resources to make informed proxy voting decisions that align with their shareholders’ interests, this Article considers the use of ChatGPT to assist small investment funds, particularly small passive …

Development Of Novel Protein Digestion And Quantitation Methods For Mass Spectrometic Analysis, Yongling Ai

Dissertations

Proteins are the workhorses of biology, playing multifaceted roles in maintaining cellular function, signaling, and response to environmental cues. Understanding their abundance and dynamics is pivotal for unraveling the complexities of biological processes, which underpins the foundations of molecular and cellular biology. Accurate measurement of protein quantities provides insights into cellular homeostasis, facilitates the discovery of biomarkers, and sheds light on the molecular mechanisms of diseases, bridging the gap between the molecular intricacies of proteins and their functional consequences in health and disease. The evolution of protein quantitation methodologies, from classical colorimetric assays to sophisticated mass spectrometry-based approaches, has expanded …

Model-Based Deep Autoencoders For Clustering Single-Cell Rna Sequencing Data With Side Information, Xiang Lin

Dissertations

Clustering analysis has been conducted extensively in single-cell RNA sequencing (scRNA-seq) studies. scRNA-seq can profile tens of thousands of genes' activities within a single cell. Thousands or tens of thousands of cells can be captured simultaneously in a typical scRNA-seq experiment. Biologists would like to cluster these cells for exploring and elucidating cell types or subtypes. Numerous methods have been designed for clustering scRNA-seq data. Yet, single-cell technologies develop so fast in the past few years that those existing methods do not catch up with these rapid changes and fail to fully fulfil their potential. For instance, besides profiling transcription …

Covalent Inhibition Of Enzyme Sortase A As A New Pathway Against Bacterial Resistance Of Staphylococcus Aureus, Umyeena Bashir

Master's Theses

The continued rise of antibiotic-resistant bacteria, such as MRSA (methicillin-resistant Staphylococcus aureus), has made the discovery of novel antibiotics critical. While bacteriostatic and bactericidal antibiotics inevitably exert evolutionary pressure on bacteria to develop resistance, small molecules that target mechanisms of bacterial virulence present a promising alternative for treatment. Sortase A (Srt A), a cysteine protease of S. aureus, promotes bacterial virulence by covalently attaching proteins such as pilin to the bacterial surface, enabling bacterial adhesion to mammalian cells. Inhibitory studies of this enzyme have gained prominent interest as a new pathway for drug development since blocking this enzyme's ability to …

Cross-Language Tourism News Retrieval System Using Google Translate Api On Sebi Search Engine, H. Husni, Arif Muntasa, Sigit Susanto Putro, Zulfi Osman

Elinvo (Electronics, Informatics, and Vocational Education)

Cross-Language Information Retrieval (CLIR) is responsible for retrieving information stored in a language different from the language of the query provided by the user. Some translation methods commonly used in CLIR are Dictionary, Parallel corpora, Comparable corpora, Machine translator, Ontology, and Transitive-based. The query must be translated to the target language, followed by preprocessing and calculating the similarity between the query and all documents in the corpus. The problem is the time and accuracy of query translation. Moreover, the queries are not written as complete sentences according to certain language rules. Stemming, for example, every language has its own method. …

Comparison Of Support Vector Machine (Svm), K-Nearest Neighbor (K-Nn), And Stochastic Gradient Descent (Sgd) For Classifying Corn Leaf Disease Based On Histogram Of Oriented Gradients (Hog) Feature Extraction, Firdaus Solihin, Muhammad Syarief, Eka Mala Sari Rochman, Aeri Rachmad

Elinvo (Electronics, Informatics, and Vocational Education)

Image classification involves categorizing an image's pixels into specific classes based on their unique characteristics. It has diverse applications in everyday life. One such application is the classification of diseases on corn leaves. Corn is a widely consumed staple food in Indonesia, and healthy corn plants are crucial for meeting market demands. Currently, disease identification in corn plants relies on manual checks, which are time-consuming and less effective. This research aims to automate disease identification on corn leaves using the Support Vector Machine (SVM), K-Nearest Neighbor (K-NN) with K=2, and Stochastic Gradient Descent (SGD) algorithms. The classification process utilizes the …

A Comparison Of Opennmt Sequence Model For Indonesian Automatic Question Generation, Yuniar Indrihapsari, Handaru Jati, N. Nurkhamid, Ratna Wardani, Pradana Setialana, Muhamad Izzudin Mahali, Danang Wijaya, Dhista Dwi Nur Ardiansyah, Satya Adhiyaksa Ardy, Maria Bernadetha Charlotta Wonda Tiala, Andi Hakim Al-Khawarizmi, Widya Ardiyanto

Elinvo (Electronics, Informatics, and Vocational Education)

Evaluation of learners is a crucial aspect of the educational system. However, creating evaluation instruments is a process that demands teachers' time and energy. The researcher developed the Indonesia Automatic Question Generator in this study using an architecture modified from past studies. The primary goals of this project are (1) to construct an AQG tool utilizing the OpenNMT series and (2) to analyze and compare the model's performance. As a data source, this study employs the SQuAD 2.0 dataset and numerous sequence techniques, including BiGRU, BiLSTM, and Transformer. The researcher trained the models using OpenNMT-py and Google Collaboratory. This approach …

Classification Of Corn Seed Quality Using Residual Network With Transfer Learning Weight, Meidya Koeshardianto, Wahyudi Agustiono, Wahyudi Setiawan

Elinvo (Electronics, Informatics, and Vocational Education)

Corn is one of the main ingredients in farm animal feed. Currently, corn is preferable because widely available and cheaper in the market than others. However, it needs quality control on corn production. The company that manufactures animal feed has certain quality standards to receive corn material. On the other hand, the quality of corn produced varies greatly. Thus, quality control when receiving corn from suppliers greatly affects the quality of animal feed. The quality of feed ingredients is classified into physical properties and analytical values. Physical properties are determined so that the resulting corn can be accepted or rejected, …

Lithium Tetraborate As A Neutron Scintillation Detector: A Review, Elena Echeverria, John W. Mcclory, Lauren Samson, Katherine Shene, Juan A. Colon Santana, Yaroslav V. Burak, Volodymyr T. Adamiv, Ihor M. Teslyuk, Lu Wang, Wai-Ning Mei, Kyle A. Nelson, Douglas S. Mcgregor, Peter A. Dowben, Carolina C. Ilie, James C. Petrosky, Archit Dhingra

Faculty Publications

The electronic structure and translucent nature of lithium tetraborate (Li₂B₄O₇) render it promising as a scintillator medium for neutron detection applications. The inherently large neutron capture cross-section due to ¹⁰B and ⁶Li isotopes and the ease with which Li₂B₄O₇ can be enriched with these isotopes, combined with the facile inclusion of rare earth dopants (occupying the Li⁺ sites), are expected to improve the luminescent properties, as well as the neutron detection efficiency, of Li₂B₄O₇. The electronic structure of both doped …

Preface, Anne Greene, Martin Lipa, Bill Paulson

Level 3

No abstract provided.

Balancing Quality Assurance & Innovation In Pharma, Emma Ramnarine

Level 3

At the Pharmaceutical Regulatory Science Team (PRST) workshop on ICH Q9(R1), held at the Technological University Dublin in early June 2023, Boehringer Ingelheim US Biopharma Operations Product Management & Development Operations Head Emma Ramnarine shared her insights on balancing quality assurance and innovation in pharmaceutical manufacturing. She addressed: ● patient-centered transformation ● a watershed moment in her career ● understanding the drug shortage problem ● disruptive collaboration, and ● systems thinking

approaches. Click here for the slides accompanying Ramnarine’s remarks. She connected some of her remarks for the pharmaceutical industry to those made in the previous talk by Ed Hoffman, …

Quality Reborn, Anders Vinther

Level 3

It is time for Quality leaders to not only fulfill the traditional role of ensuring cGMP compliance within the company but also take the Quality profession to the level of business leadership like Deming did in Japan after World War II. FDA has recently stated that they have low confidence in quality management maturity of the pharmaceutical industry.

For quality leaders to also become good business leaders we must educate them in ways that are different from what we currently do. The education should be in the 6 areas

• Visibly Demonstrating Responsibility of Quality
• Risk-Informed Decision Making and Communication
• Engaging …

Leveraging Advanced Analytics In The Pharmaceutical Industry, Patrick O'Sullivan

Level 3

This article is a transcribed and lightly edited version of Patrick O’Sullivan’s oral presentation to a seminar hosted on 1 June 2023 by the Pharmaceutical Regulatory Science Team (PRST), TU Dublin, titled ICH Q9(R1): The Next Frontier – An audience with international thought leaders exploring how the effective use of knowledge can enhance QRM outcomes to benefit the patient. Patrick presented an overview of how one could leverage advanced analytics in the pharmaceutical Industry.

Risk-Based Decision-Making – Using Knowledge Of Risk Throughout The Lifecycle, Michael Schousboe

Level 3

This article is based on a presentation given at the event ICH Q9(R1): The Next Frontier hosted by TU Dublin, Grangegorman 01-June-2023

An audience with international thought leaders exploring how the effective use of knowledge can enhance QRM outcomes to benefit the patient

Valerie Mulholland On Improving Rbdm Effectiveness, Valerie Mulholland

Level 3

No abstract provided.

Achieving Warranted Acceptance Of Biotechnologies, Emily Grayek, Baruch Fischhoff

Level 3

The U.S. has faced long-standing shortages of generic drugs, causing negative health effects and spikes in drug costs. To address these shortages, investments in critical technologies and policies to support their adoption will be needed. The success of these technologies and policies depends on public acceptance. We studied public acceptance using the mental model approach, which identifies gaps in understanding that can be addressed with communications. We began with semi-structured interviews with experts in pharmaceutical manufacturing. Based on these interviews, we developed and conducted surveys of the general public, physicians, and pharmacists. Similar strategies could be applied to improve communications …

Exploring The Role Of Knowledge In The Pharma Workplace Of The Future: An Interactive Workshop Exploring Culture, Km And Opex, Stephanie Friedrichsen, Nuala Calnan (Editor), Martin J. Lipa

Level 3

This article presents a summary of an interactive workshop facilitated by Nuala Calnan and Stephanie Friedrichsen during the conference: ‘ICH Q9(R1): The Next Frontier’ held in Technological University Dublin, Ireland, on 1 June 2023. The summary was prepared by the workshop facilitators in conjunction with Martin Lipa who was a participant at the workshop. The article is written to give a high-level overview of the discussions which took place during the workshop and is not intended to be a complete representation of all the activities, insights and findings.

Regulators Are Exploring With Industry How To Strengthen Quality Risk Management Practices, With Revision Of Ich Q9 A Key Focal Point, ( Ipq )

Level 3

No abstract provided.

Agenda From June 1st Conference

Level 3

No abstract provided.

Links To Prst Past Monographs And Level 3 Special Editions

Level 3

No abstract provided.

Speaker Bios

Level 3

No abstract provided.

Ipq Descriptor

Level 3

No abstract provided.

Ipq Bibliography Pac Km Qrm 2010 - 2023

Level 3

No abstract provided.

Relative Comparison Of Modern Computing To Computer Technology Of Ages, Iwasan D. Kejawa Dr., Hailly Rubio Ms.

School of Computing: Faculty Publications

Abstract

Abstract

Are there differences and similarities between the computer technology of today and yesterdays. Research had shown that there had been tremendous improvements from the computers of ages (traditional Computers) as we enter the 21st century. Both the physicality and the functionalities of computers have changed but some remain the same. The memory capacity and functions have changed, but all are still based on the old concepts of yesteryears.

Breaking Down Computer Networking Instructional Videos: Automatic Summarization With Video Attributes And Language Models, Totok Sukardiyono, Muhammad Irfan Luthfi, Nisa Dwi Septiyanti

Elinvo (Electronics, Informatics, and Vocational Education)

Instructional videos have become a popular tool for teaching complex topics in computer networking. However, these videos can often be lengthy and time-consuming, making it difficult for learners to obtain the key information they need. In this study, we propose an approach that leverages automatic summarization and language models to generate concise and informative summaries of instructional videos. To enhance the performance of the summarization algorithm, we also incorporate video attributes that provide contextual information about the video content. Using a dataset of computer networking tutorials, we evaluate the effectiveness of the proposed method and show that it significantly improves …

Soybean Collect Recommender Based On Distance And Productivity Cluster Using K-Means Clustering And Simple Addictive Weighting Method, Mega Wahyu Ningtyas, Feddy Setio Pribadi

Elinvo (Electronics, Informatics, and Vocational Education)

Soybeans are an essential agricultural product that is one of the primary food sources in Indonesia, such as tempeh, tofu, soy milk, soy sauce, and other preparations. However, production yields, harvested land area, and soybean productivity in each district or city in Central Java Province vary widely. Differences in soybean productivity in each area are due to production factors such as area, use of fertilizers, seeds, and labor. This study tries to provide recommendations for soybean harvesting based on the distance and productivity of an area using K-means clustering and the simple addictive weighting method. In the Central Java Province, …