Physical Sciences and Mathematics Commons^™

Measurement Of Branching Fractions And Cp Asymmetries For D+S → D + S → K+ (Η,Π;0) And D + S →Π + (Η;Π0) Decays At Belle, Y. Guan, A.J. Schwartz, K. Kinoshita, I. Adachi, H. Aihara, S. Al Said, D. M. Asner, H. Atmacan, V. Aulchenko, T. Aushev, R. Ayad, V. Babu, P. Behera, J. Bennett, M. Bessner, V. Bhardwaj, B. Bhuyan, T. Bilka, J. Biswal, Milind Purohit, Et. Al.

Faculty Publications

We report measurements of the branching fractions and CP asymmetries for D⁺ _s → Kþη, Dþ s → K⁺π⁰, and D⁺ _s → πþη decays, and the branching fraction for Dþ s → π⁺π⁰. Our results are based on a data sample corresponding to an integrated luminosity of 921 fb⁻¹ collected by the Belle detector at the KEKB e⁺e⁻ asymmetric-energy collider. Our measurements of CP asymmetries in these decays are the most precise to date; no evidence for CP violation is found.

Gwtc-2: Compact Binary Coalescences Observed By Ligo And Virgo During The First Half Of The Third Observing Run, R. Abbott, T. D. Abbott, S. Abraham, Teviet Creighton, Mario C. Diaz, Soma Mukherjee, Volker Quetschke, Malik Rakhmanov, Karla E. Ramirez, W. H. Wang

Physics and Astronomy Faculty Publications and Presentations

We report on gravitational-wave discoveries from compact binary coalescences detected by Advanced LIGO and Advanced Virgo in the first half of the third observing run (O3a) between 1 April 2019 15∶00 UTC and 1 October 2019 15∶00 UTC. By imposing a false-alarm-rate threshold of two per year in each of the four search pipelines that constitute our search, we present 39 candidate gravitational-wave events. At this threshold, we expect a contamination fraction of less than 10%. Of these, 26 candidate events were reported previously in near-real time through gamma-ray coordinates network notices and circulars; 13 are reported here for the …

Landscape-Based Mutational Sensitivity Cartography And Network Community Analysis Of The Sars-Cov-2 Spike Protein Structures: Quantifying Functional Effects Of The Circulating D614g Variant, Gennady M. Verkhivker, Steve Agajanian, Deniz Yasar Oztas, Grace Gupta

Mathematics, Physics, and Computer Science Faculty Articles and Research

We developed and applied a computational approach to simulate functional effects of the global circulating mutation D614G of the SARS-CoV-2 spike protein. All-atom molecular dynamics simulations are combined with deep mutational scanning and analysis of the residue interaction networks to investigate conformational landscapes and energetics of the SARS-CoV-2 spike proteins in different functional states of the D614G mutant. The results of conformational dynamics and analysis of collective motions demonstrated that the D614 site plays a key regulatory role in governing functional transitions between open and closed states. Using mutational scanning and sensitivity analysis of protein residues, we identified the stability …

Impact Of Neoantigen Expression And T-Cell Activation On Breast Cancer Survival, Wenjing Li, Amei Amei, Francis Bui, Saba Norouzifar, Lingeng Lu, Zuoheng Wang

Mathematical Sciences Faculty Research

Neoantigens are derived from tumor-specific somatic mutations. Neoantigen-based syn-thesized peptides have been under clinical investigation to boost cancer immunotherapy efficacy. The promising results prompt us to further elucidate the effect of neoantigen expression on patient survival in breast cancer. We applied Kaplan–Meier survival and multivariable Cox regression models to evaluate the effect of neoantigen expression and its interaction with T-cell activation on overall survival in a cohort of 729 breast cancer patients. Pearson’s chi-squared tests were used to assess the relationships between neoantigen expression and clinical pathological variables. Spearman correlation analysis was conducted to identify correlations between neoantigen expression, mutation …

Diversity Of Desert Rodent Communities Under Different Disturbances And Scales In Alashan Desert, Inner Mongolia, Heping Fu, Xiaodong Wu, Fushun Zhang

IGC Proceedings (1993-2023)

No abstract provided.

Forage Yield Of Grass And Legume Entries In The Establishing Year In A Dry Tropical Area, Enrique Cortés-Díaz, Angel Ramon‐Garay, Fernando Tellez‐Hernández, José L. Zaragoza-Ramírez, Pedro A. Martínez-Hernández

IGC Proceedings (1993-2023)

No abstract provided.

Different Reactions Of Plants And Insect Taxa To Reduction Of Stocking Rate: A Concrete Reason To Promote Habitat Heterogeneity In Grazing Systems, Bertrand Dumont, Anne Farruggia, J.-P. Garel

IGC Proceedings (1993-2023)

No abstract provided.

Penalized Likelihood Estimation Of Gamma Distributed Response Variable Via Corrected Solution Of Regression Coefficients, Rasaki Olawale Olanrewaju

Journal of Modern Applied Statistical Methods

A Gamma distributed response is subjected to regression penalized likelihood estimations of Least Absolute Shrinkage and Selection Operator (LASSO) and Minimax Concave Penalty via Generalized Linear Models (GLMs). The Gamma related disturbance controls the influence of skewness and spread in the corrected path solutions of the regression coefficients.

Pairwise Balanced Designs From Cyclic Pbib Designs, D. K. Ghosh, N. R. Desai, Shreya Ghosh

Journal of Modern Applied Statistical Methods

A pairwise balanced designs was constructed using cyclic partially balanced incomplete block designs with either (λ1 – λ2) = 1 or (λ2 – λ1) = 1. This method of construction of Pairwise balanced designs is further generalized to construct it using cyclic partially balanced incomplete block design when |(λ1 – λ2)| = p. The methods of construction of pairwise balanced designs was supported with examples. A table consisting parameters of Cyclic PBIB designs and its corresponding constructed pairwise balanced design is also included.

Generalized Ratio-Cum-Product Estimator For Finite Population Mean Under Two-Phase Sampling Scheme, Gajendra Kumar Vishwakarma, Sayed Mohammed Zeeshan

Journal of Modern Applied Statistical Methods

A method to lower the MSE of a proposed estimator relative to the MSE of the linear regression estimator under two-phase sampling scheme is developed. Estimators are developed to estimate the mean of the variate under study with the help of auxiliary variate (which are unknown but it can be accessed conveniently and economically). The mean square errors equations are obtained for the proposed estimators. In addition, optimal sample sizes are obtained under the given cost function. The comparison study has been done to set up conditions for which developed estimators are more effective than other estimators with novelty. The …

Two Different Classes Of Shrinkage Estimators For The Scale Parameter Of The Rayleigh Distribution, Talha Omer, Zawar Hussain, Muhammad Qasim, Said Farooq Shah, Akbar Ali Khan

Journal of Modern Applied Statistical Methods

Shrinkage estimators are introduced for the scale parameter of the Rayleigh distribution by using two different shrinkage techniques. The mean squared error properties of the proposed estimator have been derived. The comparison of proposed classes of the estimators is made with the respective conventional unbiased estimators by means of mean squared error in the simulation study. Simulation results show that the proposed shrinkage estimators yield smaller mean squared error than the existence of unbiased estimators.

A Simple Random Sampling Modified Dual To Product Estimator For Estimating Population Mean Using Order Statistics, Sanjay Kumar, Priyanka Chhaparwal

Journal of Modern Applied Statistical Methods

Bandopadhyaya (1980) developed a dual to product estimator using robust modified maximum likelihood estimators (MMLE’s). Their properties were obtained theoretically and supported through simulations studies with generated as well as one real data set. Robustness properties in the presence of outliers and confidence intervals were studied.

Extending Singh-Maddala Distribution, Mohamed Ali Ahmed

Journal of Modern Applied Statistical Methods

A new distribution, the exponentiated transmuted Singh-Maddala distribution (ETSM), is presented, and three important special distributions are illustrated. Some mathematical properties are obtained, and parameters estimation method is applied using maximum likelihood. Illustrations based on random numbers and a real data set are given.

How To Apply Multiple Imputation In Propensity Score Matching With Partially Observed Confounders: A Simulation Study And Practical Recommendations, Albee Ling, Maria Montez-Rath, Maya Mathur, Kris Kapphahn, Manisha Desai

Journal of Modern Applied Statistical Methods

Propensity score matching (PSM) has been widely used to mitigate confounding in observational studies, although complications arise when the covariates used to estimate the PS are only partially observed. Multiple imputation (MI) is a potential solution for handling missing covariates in the estimation of the PS. However, it is not clear how to best apply MI strategies in the context of PSM. We conducted a simulation study to compare the performances of popular non-MI missing data methods and various MI-based strategies under different missing data mechanisms. We found that commonly applied missing data methods resulted in biased and inefficient estimates, …

The Hubble Pancet Program: Long-Term Chromospheric Evolution And Flaring Activity Of The M Dwarf Host Gj 3470★, Vincent Bourrier, Leonardo A. Dos Santos, Jorge Sanz-Forcada, Antonio García Muñoz, Gregory W. Henry, Panayotis Lavvas, Alain Lecavelier, Mercedes López-Morales, Thomas Mikal-Evans, David K. Sing, Hannah R. Wakeford, David Ehrenreich

Information Systems and Engineering Management Research Publications

Neptune-size exoplanets seem particularly sensitive to atmospheric evaporation, making it essential to characterize the stellar high-energy radiation that drives this mechanism. This is particularly important with M dwarfs, which emit a large and variable fraction of their luminosity in the ultraviolet and can display strong flaring behavior. The warm Neptune GJ 3470b, hosted by an M2 dwarf, was found to harbor a giant exosphere of neutral hydrogen thanks to three transits observed with the Hubble Space Telescope Imaging Spectrograph (HST/STIS). Here we report on three additional transit observations from the Panchromatic Comparative Exoplanet Treasury program, obtained with the HST Cosmic …

Examining Dimensions Of Patient Satisfaction With Telemedicine, Robert Garcia

College of Computing and Digital Media Dissertations

During the outbreak of the novel coronavirus (COVID-19) medical institutions and practitioners have drastically increased their adoption of telemedicine. The proliferation of telemedicine systems has sparked renewed interest among IS researchers in evaluating its usage. One of the main indicators used to measure the success of telemedicine services is patient satisfaction. Yet several problems exist with current methods used to evaluate telemedicine satisfaction. Patient satisfaction with telemedicine is frequently evaluated using either single question items or handmade instruments that are seldom assessed for validity. While telemedicine satisfaction is typically evaluated through single measures, satisfaction is considered a complex and multidimensional …

A New Right-Skewed Upside Down Bathtub Shaped Heavy-Tailed Distribution And Its Applications, Sandeep Kumar Maurya, Sanjay K. Singh, Umesh Singh

Journal of Modern Applied Statistical Methods

A one parameter right skewed, upside down bathtub type, heavy-tailed distribution is derived. Various statistical properties and maximum likelihood approaches for estimation purpose are studied. Five different real data sets with four different models are considered to illustrate the suitability of the proposed model.

On The Level Of Precision Of A Heterogeneous Transfer Function In A Statistical Neural Network Model, Christopher Godwin Udomboso

Journal of Modern Applied Statistical Methods

A heterogeneous function of the statistical neural network is presented from two transfer functions: symmetric saturated linear and hyperbolic tangent sigmoid. The precision of the derived heterogeneous model over their respective homogeneous forms are established, both at increased sample sizes hidden neurons. Results further show the sensitivity of the heterogeneous model to increase in hidden neurons.

An Ultra-Short-Period Transiting Super-Earth Orbiting The M3 Dwarf Toi-1685, P. Bluhm, E. Pallé, K. Molaverdikhani, J. Kemmer, A. P. Hatzes, D. Kossakowski, S. Stock, J. A. Caballero, J. Lillo-Box, V. J. S. Béjar, M. G. Soto, P. J. Amado, P. Brown, C. Cadieux, R. Cloutier, K. A. Collins, K. I. Collins, M. Cortés-Contreras, R. Doyon, S. Dreizler, N. Espinoza, A. Fukui, E. González-Álvarez, T. Henning, K. Horne, S. V. Jeffers, J. M. Jenkins, Eric L.N. Jensen, A. Kaminski, J. F. Kielkopf, N. Kusakabe, M. Kürster, D. Lafrenière, R. Luque, F. Murgas, D. Montes, J. C. Morales, N. Narita, V. M. Passegger, A. Quirrenbach, P. Schöfer, S. Reffert, A. Reiners, I. Ribas, G. R. Ricker, S. Seager, A. Schweitzer, R. P. Schwarz, M. Tamura, T. Trifonov, R. Vanderspek, J. Winn, M. Zechmeister, M. R. Zapatero Osorio

Physics & Astronomy Faculty Works

Dynamical histories of planetary systems, as well as the atmospheric evolution of highly irradiated planets, can be studied by characterizing the ultra-short-period planet population, which the TESS mission is particularly well suited to discover. Here, we report on the follow-up of a transit signal detected in the TESS sector 19 photometric time series of the M3.0 V star TOI-1685 (2MASS J04342248+4302148). We confirm the planetary nature of the transit signal, which has a period of Pb = 0.6691403−0.0000021+0.0000023 d, using precise radial velocity measurements taken with the CARMENES spectrograph. From the joint photometry and radial velocity analysis, we estimate the …

Vif-Regression Screening Ultrahigh Dimensional Feature Space, Hassan S. Uraibi

Journal of Modern Applied Statistical Methods

Iterative Sure Independent Screening (ISIS) was proposed for the problem of variable selection with ultrahigh dimensional feature space. Unfortunately, the ISIS method transforms the dimensionality of features from ultrahigh to ultra-low and may result in un-reliable inference when the number of important variables particularly is greater than the screening threshold. The proposed method has transformed the ultrahigh dimensionality of features to high dimension space in order to remedy of losing some information by ISIS method. The proposed method is compared with ISIS method by using real data and simulation. The results show this method is more efficient and more reliable …

A New Generalized Family Of Distributions For Lifetime Data, Maha A. D. Aldahlan, Mohamed G. Khalil, Ahmed Z. Afify

Journal of Modern Applied Statistical Methods

A new class of continuous distributions called the generalized Burr X-G family is introduced. Some special models of the new family are provided. Some of its mathematical properties including explicit expressions for the quantile and generating functions, ordinary and incomplete moments, order statistics and Rényi entropy are derived. The maximum likelihood is used for estimating the model parameters. The flexibility of the generated family is illustrated by means of two applications to real data sets.

Jmasm 57: Bayesian Survival Analysis Of Lomax Family Models With Stan (R), Mohammed H. A. Abujarad, Athar Ali Khan

Journal of Modern Applied Statistical Methods

An attempt is made to fit three distributions, the Lomax, exponential Lomax, and Weibull Lomax to implement Bayesian methods to analyze Myeloma patients using Stan. This model is applied to a real survival censored data so that all the concepts and computations will be around the same data. A code was developed and improved to implement censored mechanism throughout using rstan. Furthermore, parallel simulation tools are also implemented with an extensive use of rstan.

Inference For Step-Stress Partially Accelerated Life Test Model With An Adaptive Type-I Progressively Hybrid Censored Data, Showkat Ahmad Lone, Ahmadur Rahman, Tanveer A. Tarray

Journal of Modern Applied Statistical Methods

Consider estimating data of failure times under step-stress partially accelerated life tests based on adaptive Type-I hybrid censoring. The mathematical model related to the lifetime of the test units is assumed to follow Rayleigh distribution. The point and interval maximum-likelihood estimations are obtained for distribution parameter and tampering coefficient. Also, the work is conducted under a traditional Type-I hybrid censoring plan (scheme). A Monte Carlo simulation algorithm is used to evaluate and compare the performances of the estimators of the tempering coefficient and model parameters under both progressively hybrid censoring plans. The comparison is carried out on the basis of …

Study Of Quasimonoenergetic Electron Bunch Generation In Self-Modulated Laser Wakefield Acceleration Using Tw Or Sub-Tw Ultrashort Laser Pulses, E. P. Maldonado, R. E. Samad, A. Bonatto, R. P. Nunes, S. Banerjee, N. D. Vieira

Department of Physics and Astronomy: Faculty Publications

This work presents a study on laser wakefield electron acceleration in the self-modulated regime (SM-LWFA) using 50-fs laser pulses with energy on the mJ scale, at λ = 0.8 μm, impinging on a thin H₂ gas jet. Particle-in-cell simulations were performed using laser peak powers ranging from sub-terawatt to a few terawatts and plasma densities varying from the relativistic self-focusing threshold up to values close to the critical density. The differences in the obtained acceleration processes are discussed. Results show that bunched electron beams with full charge on the nC scale and kinetic energy in the MeV range …

Early Assessment Of Lung Function In Coronavirus Patients Using Invariant Markers From Chest X-Rays Images, Mohamed Elsharkawy, Ahmed Sharafeldeen, Fatma Taher, Ahmed Shalaby, Ahmed Soliman, Ali Mahmoud, Mohammed Ghazal, Ashraf Khalil, Norah Saleh Alghamdi, Ahmed Abdel Khalek Abdel Razek, Eman Alnaghy, Moumen T. El-Melegy, Harpal Singh Sandhu, Guruprasad A. Giridharan, Ayman El-Baz

All Works

The primary goal of this manuscript is to develop a computer assisted diagnostic (CAD) system to assess pulmonary function and risk of mortality in patients with coronavirus disease 2019 (COVID-19). The CAD system processes chest X-ray data and provides accurate, objective imaging markers to assist in the determination of patients with a higher risk of death and thus are more likely to require mechanical ventilation and/or more intensive clinical care.To obtain an accurate stochastic model that has the ability to detect the severity of lung infection, we develop a second-order Markov-Gibbs random field (MGRF) invariant under rigid transformation (translation or …

Reinforcement Learning With Auxiliary Memory, Sterling Suggs

Theses and Dissertations

Deep reinforcement learning algorithms typically require vast amounts of data to train to a useful level of performance. Each time new data is encountered, the network must inefficiently update all of its parameters. Auxiliary memory units can help deep neural networks train more efficiently by separating computation from storage, and providing a means to rapidly store and retrieve precise information. We present four deep reinforcement learning models augmented with external memory, and benchmark their performance on ten tasks from the Arcade Learning Environment. Our discussion and insights will be helpful for future RL researchers developing their own memory agents.

Numerical Techniques And Simulations For Studying Various High Power Optical Fiber Amplifiers, Particularly For Ytterbium (Yb+3), And Thulium (Tm+3) Doped Fibers, Tathagata Goswami

Dissertations and Theses

In this dissertation we present a simplified scalar numerical model, derived from Maxwell's field equations, for the fiber laser amplifier simulations. Maxwell's equations are reduced using a technique called Coupled Mode Theory (CMT).

The reduced model is made more efficient through a new scale model, referred to as an equivalent short fiber, which captures some of the essential characteristics of a longer fiber. The equivalent short fiber can be viewed as a fiber made using artificial (nonphysical) material properties that in some sense compensates for its reduced length. The computations can be accelerated by a factor approximately equal to the …

A Method For Comparative Analysis Of Trusted Execution Environments, Stephano Cetola

Dissertations and Theses

The problem of secure remote computation has become a serious concern of hardware manufacturers and software developers alike. Trusted Execution Environments (TEEs) are a solution to the problem of secure remote computation in applications ranging from "chip and pin" financial transactions to intellectual property protection in modern gaming systems. While extensive literature has been published about many of these technologies, there exists no current model for comparing TEEs. This thesis provides hardware architects and designers with a set of tools for comparing TEEs. I do so by examining several properties of a TEE and comparing their implementations in several technologies. …

Complexes With Atomic Gold Ions: Efficient Bisligand Formation, Felix Duensing, Elisabeth Gruber, Paul Martini, Marcelo Goulart, Michael Gatchell, Bilal Rasul, Olof E. Echt, Fabio Zappa, Masoomeh Mahmoodi-Darian, Paul Scheier

Faculty Publications

Complexes of atomic gold with a variety of ligands have been formed by passing helium nanodroplets (HNDs) through two pickup cells containing gold vapor and the vapor of another dopant, namely a rare gas, diatomic molecule (H₂, N₂, O₂, I₂, P₂), or various polyatomic molecules (H₂O, CO₂, SF₆, C₆H₆, adamantane, imidazole, di-cyclopentadiene, and fullerene). The doped HNDs were irradiated by electrons; ensuing cations were identified in a high-resolution mass spectrometer. Anions were detected for benzene, di-cyclopentadiene, and fullerene. For most …

Pegylation Stabilizes The Conformation Of Proteins And The Noncovalent Interactions Within Them, Steven R. E. Draper

Theses and Dissertations

PEGylation has been used for decades to enhance the pharmacokinetic properties of protein therapeutics. This method has been effective at increasing the serum half-life of these drugs, but the mechanism of how it does this is unclear. Chapter 1 is an introduction to the methods of PEGylation. In chapter 2 we show that the effect of PEGylation on the conformational stability of the WW domain differs based on amino acid linker and conjugation site. We show that all positions in the WW domain that were tested can be stabilized by at least one amino acid linker. The rate of proteolysis …