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Articles 6421 - 6450 of 302425

Full-Text Articles in Physical Sciences and Mathematics

Nonlinear Dynamics Of Mountain Pine Beetle Populations: Discussion Of Forestry Policy, A Survey Of Existing Mathematical Models, And Code Base Demonstration, Scott A. Strong, Maya Maes-Johnson Jan 2024

Nonlinear Dynamics Of Mountain Pine Beetle Populations: Discussion Of Forestry Policy, A Survey Of Existing Mathematical Models, And Code Base Demonstration, Scott A. Strong, Maya Maes-Johnson

CODEE Journal

This article presents existing mathematical models associated with mountain pine beetle populations in lodgepole pine forests, whose reproductive cycle requires the destruction of colonized host trees, decreasing timber availability/quality, and providing fuel sources for wildfires. With the existence of a positive-feedback loop with environmental warming, the need for intervention and management is clear. However, the legislative responses to the focusing events from our 2000-2010 North American epidemics are characterized as under-leveraged. While the reasons for this are multifaceted, increasing the capacity of STEM-informed individuals to take part in quantitative modeling of the underlying ecosystem generates awareness and provides pathways connecting …

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Solar Panels, Euler’S Method And Community-Based Projects: Connecting Differential Equations With Climate Change, Victor J. Donnay Jan 2024

Solar Panels, Euler’S Method And Community-Based Projects: Connecting Differential Equations With Climate Change, Victor J. Donnay

CODEE Journal

How does mathematics connect with the search for solutions to the climate emergency? One simple connection, which can be explored in an introductory differential equations course, can be found by analyzing the energy generated by solar panels or wind turbines. The power generated by these devices is typically recorded at standard time intervals producing a data set which gives a discrete approximation to the power function $P(t)$. Using numerical techniques such as Euler’s method, one can determine the energy generated. Here we describe how we introduce the topic of solar power, apply Euler’s method to determine the energy generated, and …

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To Open Or Not To Open: Developing A Covid-19 Model Specific To Small Residential Campuses, Christina Joy Edholm, Maryann Hohn, Nicole Lee Falicov, Emily Lee, Lily Natasha Wartman, Ami Radunskaya Jan 2024

To Open Or Not To Open: Developing A Covid-19 Model Specific To Small Residential Campuses, Christina Joy Edholm, Maryann Hohn, Nicole Lee Falicov, Emily Lee, Lily Natasha Wartman, Ami Radunskaya

CODEE Journal

In May 2020, administrators of residential colleges struggled with the decision of whether or not to open their campuses in the Fall semester of 2020. To help guide this decision, we formulated an ODE model capturing the dynamics of the spread of COVID-19 on a residential campus. In order to provide as much information as possible for administrators, the model accounts for the different behaviors, susceptibility, and risks in the various sub-populations that make up the campus community. In particular, we start with a traditional SEIR model and add compartments representing relevant variables, such as quarantine compartments and a hospitalized …

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Fitting A Covid-19 Model Incorporating Senses Of Safety And Caution To Local Data From Spartanburg County, South Carolina, D. Chloe Griffin, Amanda Mangum Jan 2024

Fitting A Covid-19 Model Incorporating Senses Of Safety And Caution To Local Data From Spartanburg County, South Carolina, D. Chloe Griffin, Amanda Mangum

CODEE Journal

Common mechanistic models include Susceptible-Infected-Removed (SIR) and Susceptible-Exposed-Infected-Removed (SEIR) models. These models in their basic forms have generally failed to capture the nature of the COVID-19 pandemic's multiple waves and do not take into account public policies such as social distancing, mask mandates, and the ``Stay-at-Home'' orders implemented in early 2020. While the Susceptible-Vaccinated-Infected-Recovered-Deceased (SVIRD) model only adds two more compartments to the SIR model, the inclusion of time-dependent parameters allows for the model to better capture the first two waves of the COVID-19 pandemic when surveillance testing was common practice for a large portion of the population. We find …

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Applying The Sir Model: Can Students Advise The Mayor Of A Small Community?, Carrin Goosen, Mark I. Nelson, Mahime Watanabe Jan 2024

Applying The Sir Model: Can Students Advise The Mayor Of A Small Community?, Carrin Goosen, Mark I. Nelson, Mahime Watanabe

CODEE Journal

This is an account of a modelling scenario that uses the sir epidemic model. It was used in a third year applied mathematics subject. All students were enrolled in a mathematics degree of some type. Students are presented with the results of a test carried out on 100 individuals in a community containing 3000 people. From this they determined the number of infectious and recovered individuals in the population. Given the per capita recovery rate and making a suitable assumption about the number of infectious individuals at the start of the epidemic, they then estimate the infectious contact rate and …

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Differential Equations For A Changing World:How To Engage Students In Learning And Applying Differential Equations, Biyong Luo Jan 2024

Differential Equations For A Changing World:How To Engage Students In Learning And Applying Differential Equations, Biyong Luo

CODEE Journal

In this article, I share my decade-long experience teaching an intensive five-week summer Differential Equation course covering complex topics and tips for creating an interactive and supportive learning environment to optimize student engagement. This article provides my detailed approach to planning and teaching an asynchronous course with rigor and flexibility for each student. An interactive teaching approach and variety of learning activities will augment students’ mathematical fluency and appreciation of the importance of differential equations in modeling a wide variety of real-world situations with special attention to ways differential equations can be relevant to creating public policy.

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Modeling Aircraft Takeoffs, Catherine Cavagnaro Jan 2024

Modeling Aircraft Takeoffs, Catherine Cavagnaro

CODEE Journal

Real-world applications can demonstrate how mathematical models describe and provide insight into familiar physical systems. In this paper, we apply techniques from a first-semester differential equations course that shed light on a problem from aviation. In particular, we construct several differential equations that model the distance that an aircraft requires to become airborne. A popular thumb rule that pilots have used for decades appears to emanate from one of these models. We will see that this rule does not follow from a representative model and suggest a better method of ensuring safety during takeoff. Aircraft safety is definitely a matter …

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Odes And Mandatory Voting, Christoph Borgers, Natasa Dragovic, Anna Haensch, Arkadz Kirshtein, Lilla Orr Jan 2024

Odes And Mandatory Voting, Christoph Borgers, Natasa Dragovic, Anna Haensch, Arkadz Kirshtein, Lilla Orr

CODEE Journal

This paper presents mathematics relevant to the question whether voting should be mandatory. Assuming a static distribution of voters’ political beliefs, we model how politicians might adjust their positions to raise their share of the vote. Various scenarios can be explored using our app at https: //centrism.streamlit.app/. Abstentions are found to have great impact on the dynamics of candidates, and in particular to introduce the possibility of discontinuous jumps in optimal candidate positions. This is an unusual application of ODEs. We hope that it might help engage some students who may find it harder to connect with the more customary …

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Raising Student Awareness Of Environmental Issues Via Writing Assignments With Differential Equations, Michelle L. Ghrist Jan 2024

Raising Student Awareness Of Environmental Issues Via Writing Assignments With Differential Equations, Michelle L. Ghrist

CODEE Journal

In this paper, I discuss two environmentally-focused writing assignments that I developed and implemented in recent integral calculus and differential equations courses. These models of carbon storage and PCB’s in a river provide interesting applications of one-compartment mixing problems. The assignments were intended to focus student attention on sustainability concerns while also developing other essential skills. I discuss these assignments and their effect on my students’ technical writing and environmental awareness. Detailed introductory instructions and mostly complete solutions to these assignments appear in the appendices, to include sample student work.

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Preliminary Results Of The Great Kahramanmaraş 6 February 2023 Earthquakes (Mw 7.7 And 7.6) And 20 February 2023 Antakya Earthquake (Mw 6.4), Eastern Türkiye, Şule Gürboğa, Önder Kayadi̇bi̇, Hafi̇ze Akilli, Serap Arikan, Sevi̇lay Tan Jan 2024

Preliminary Results Of The Great Kahramanmaraş 6 February 2023 Earthquakes (Mw 7.7 And 7.6) And 20 February 2023 Antakya Earthquake (Mw 6.4), Eastern Türkiye, Şule Gürboğa, Önder Kayadi̇bi̇, Hafi̇ze Akilli, Serap Arikan, Sevi̇lay Tan

Turkish Journal of Earth Sciences

The first MW 7.7 and second MW 7.6 Kahramanmaraş earthquakes were the strongest tectonic events in Eastern Türkiye since the MW 7.9 Erzincan earthquake in 1939. The first and second events occurred on the Pazarcık and Çardak segments of the East Anatolian Fault System, respectively. A subsequent significant earthquake of MW 6.4 occurred in the Antakya fault zone. We summarize preliminary earthquake data and share our previous field observations to better understand the mechanism and provide scientific consequences for future investigations and layout planning. After combining the field observations, kinematic analysis of fault surfaces, investigations of orthophotos, characteristics of mainshocks, …

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Response Of Water Resources To The Kahramanmaraş Earthquakes (Mw 7.7 And Mw 7.6) That Occurred On February 6, 2023, On The East Anatolian Fault Zone (Türkiye), Celaletti̇n Şi̇mşek, Görkem Akinci, Okan Fistikoğlu, Kerem Canli, Hasan Sözbi̇li̇r, Azi̇ze Ayol, Efem Bi̇lgi̇ç Jan 2024

Response Of Water Resources To The Kahramanmaraş Earthquakes (Mw 7.7 And Mw 7.6) That Occurred On February 6, 2023, On The East Anatolian Fault Zone (Türkiye), Celaletti̇n Şi̇mşek, Görkem Akinci, Okan Fistikoğlu, Kerem Canli, Hasan Sözbi̇li̇r, Azi̇ze Ayol, Efem Bi̇lgi̇ç

Turkish Journal of Earth Sciences

On February 6, 2023, two destructive earthquakes of 7.7 MW and 7.6 MW occurred in Pazarcık (Kahramanmaraş) and Elbistan (Kahramanmaraş) at 04:17 and 13:24 hours, respectively. These earthquakes caused a surface rupture with a total length of 450 km in the region with an average displacement of 3 m between the Arabian and Anatolian plates. This study was conducted to investigate the physical deformation of the aquifer system and the current water quality characteristics in the affected region utilizing field observations and on-site analysis of water sources and tap water. The study revealed significant physical changes in the karstic springs …

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Approved Butte Priority Soils Operable Unit (Bpsou) Unreclaimed And Insufficiently Reclaimed Sites Request For Information 2022-01, Mike Mcanulty Jan 2024

Approved Butte Priority Soils Operable Unit (Bpsou) Unreclaimed And Insufficiently Reclaimed Sites Request For Information 2022-01, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

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Investigation Of Earthquake Sequence And Stress Transfer In The Eastern Anatolia Fault Zone By Coulomb Stress Analysis, Hamdi̇ Alkan, Aydin Büyüksaraç, Özcan Bektaş Jan 2024

Investigation Of Earthquake Sequence And Stress Transfer In The Eastern Anatolia Fault Zone By Coulomb Stress Analysis, Hamdi̇ Alkan, Aydin Büyüksaraç, Özcan Bektaş

Turkish Journal of Earth Sciences

A devastating earthquake with a magnitude of (Mw = 7.7) occurred on February 06, 2023, in the Pazarcık segment of the Eastern Anatolian Fault Zone, which has not shown major earthquake activity for a long time. On the same day, another earthquake with a magnitude of (Mw = 7.6) occurred in Ekinözü-Elbistan (Kahramanmaraş) in the northwest. Three more earthquakes with magnitudes of Mw = 6.6, Mw = 5.9, and ML = 5.7 occurred on the same day, and significant damage, loss of life, and property occurred in 11 provinces and districts. A sixth earthquake occurred with Mw = 6.4 magnitude …

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Tepehan Rockslide: A Large-Scale Earthquake-Induced Geological Structure Formed By Mw:7.8 Kahramanmaraş (Pazarcık) Earthquake, Türkiye, Ökmen Sümer Jan 2024

Tepehan Rockslide: A Large-Scale Earthquake-Induced Geological Structure Formed By Mw:7.8 Kahramanmaraş (Pazarcık) Earthquake, Türkiye, Ökmen Sümer

Turkish Journal of Earth Sciences

Three devastating and powerful earthquakes hit the southeastern and eastern parts of Turkey and the northestern part of Syria in February of 2023, causing many earthquake-induced slope movements. One of these major mass movements is called the “Tepehan Rockslide”, which was formed by the first Mw: 7.8 earthquake on February 6th, 2023 at Pazarcık (Kahramanmaraş) located in the Altınözü district of Hatay province. The rockslide involved the movement of Middle Miocene basement rocks that consist of clayey limestone, marl, and fine-grained clastic sedimentary rocks. The morphogenetic evaluation of the structure reveals that the Tepehan Rockslide is a very rapidly developed …

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Soil Liquefaction And Subsidence Disaster In İskenderun Related To The 6 February 2023 Pazarcık (Mw: 7.7) And 20 February Defne (Mw: 6.4) Earthquakes, Türkiye, Hüseyi̇n Öztürk, Craig A. Davis, İbrahi̇m Kuşku, Süleyman Dalğiç, Cem Kasapçi, Muharrem Alper Şengül Jan 2024

Soil Liquefaction And Subsidence Disaster In İskenderun Related To The 6 February 2023 Pazarcık (Mw: 7.7) And 20 February Defne (Mw: 6.4) Earthquakes, Türkiye, Hüseyi̇n Öztürk, Craig A. Davis, İbrahi̇m Kuşku, Süleyman Dalğiç, Cem Kasapçi, Muharrem Alper Şengül

Turkish Journal of Earth Sciences

The Mw 7.7 Pazarcık earthquake on February 06, 2023, struck southern Türkiye, causing typical liquefaction along the shores of İskenderun Bay. This liquefaction was characterized by lateral spreading, subsidence, and flooding. Subsidence-triggered sand ejecta, water flows, and opening cracks were identified in areas spanning approximately 2 km in length and 300 m in width. Based on coastal references such as lighthouses or harbor platforms, settlements of 0.8 m and lateral spreading of 0.4% were recorded along the coastal zone following the Pazarcık earthquake. According to camera recordings, liquefaction-related water and silty sand outflows occurred 29 min after the earthquake. The …

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Surface Rupture During The 6th Of February 2023 Mw 7.6 Elbistan-Ekinözü (Kahramanmaraş) Earthquake: Implications For Fault Rupture Dynamics Along The Northern Branch Of East Anatolian Fault Zone, Mustafa Softa, Fi̇kret Koçbulut, Eli̇f Akgün, Ercan Aksoy, Hasan Sözbi̇li̇r, Orhan Tatar, Volkan Karabacak, Çağlar Özkaymak, Mehmet Utku, Özkan Cevdet Özdağ, Recep Çakir, Ahmet Demi̇r, Gökhan Arslan Jan 2024

Surface Rupture During The 6th Of February 2023 Mw 7.6 Elbistan-Ekinözü (Kahramanmaraş) Earthquake: Implications For Fault Rupture Dynamics Along The Northern Branch Of East Anatolian Fault Zone, Mustafa Softa, Fi̇kret Koçbulut, Eli̇f Akgün, Ercan Aksoy, Hasan Sözbi̇li̇r, Orhan Tatar, Volkan Karabacak, Çağlar Özkaymak, Mehmet Utku, Özkan Cevdet Özdağ, Recep Çakir, Ahmet Demi̇r, Gökhan Arslan

Turkish Journal of Earth Sciences

On the 6th of February 2023, Mw 7.7 Pazarcık (Kahramanmaraş) and Mw 7.6 Ekinözü (Kahramanmaraş) earthquakes that occurred in Türkiye are devastating earthquake series that filled the existing seismic gaps on East Anatolian Fault Zone on the same day. The first Mw 7.7 earthquake caught most people in their sleep and 9 h later, a second one was triggered, ending up with more than 50k death toll, widespread damage to buildings, and massive landslides. This study presents the surface rupture geometry and coseismic displacement characteristics determined with field observations immediately after February 6, 2023, Ekinözü (Kahramanmaraş, Türkiye) earthquake (Mw 7.6). …

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Splitfed-Based Patient Severity Prediction And Utility Maximization In Industrial Healthcare 4.0, Himanshu Singh, Biken Moirangthem, Ajay Pratap, Shilpi Kumari, Abhishek Kumar, Sajal K. Das Jan 2024

Splitfed-Based Patient Severity Prediction And Utility Maximization In Industrial Healthcare 4.0, Himanshu Singh, Biken Moirangthem, Ajay Pratap, Shilpi Kumari, Abhishek Kumar, Sajal K. Das

Computer Science Faculty Research & Creative Works

The healthcare industry has transitioned from traditional healthcare 1.0 to AI-powered healthcare 4.0. However, overall cost for patient treatment remains high and challenging to manage due to the absence of a centralized cost evaluation mechanism before hospital visits. Therefore, in this paper, we devise a cloud-based mechanism to calculate hospitals' star rating based on questionnaire with the application of Z-score and K∗clustering algorithm. To evaluate disease severity at cloud, splitfed technique is utilized in coordination with Wireless Body Area Network (WBAN). Finally, the cloud calculates provisional treatment costs and finds a preferable hospital with a low payable treatment cost and …

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Ode Models Of Wealth Concentration And Taxation, Bruce Boghosian, Christoph Borgers Jan 2024

Ode Models Of Wealth Concentration And Taxation, Bruce Boghosian, Christoph Borgers

CODEE Journal

We refer to an individual holding a non-negligible fraction of the country’s total wealth as an oligarch. We explain how a model due to Boghosian et al. can be used to explore the effects of taxation on the emergence of oligarchs. The model suggests that oligarchs will emerge when wealth taxation is below a certain threshold, not when it is above the threshold. The underlying mechanism is a transcritical bifurcation. The model also suggests that taxation of income and capital gains alone cannot prevent the emergence of oligarchs. We suggest several opportunities for students to explore modifications of the model.

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Using A Sand Tank Groundwater Model To Investigate A Groundwater Flow Model, Christopher Evrard, Callie Johnson, Michael A. Karls, Nicole Regnier Jan 2024

Using A Sand Tank Groundwater Model To Investigate A Groundwater Flow Model, Christopher Evrard, Callie Johnson, Michael A. Karls, Nicole Regnier

CODEE Journal

A Sand Tank Groundwater Model is a tabletop physical model constructed of plexiglass and filled with sand that is typically used to illustrate how groundwater water flows through an aquifer, how water wells work, and the effects of contaminants introduced into an aquifer. Mathematically groundwater flow through an aquifer can be modeled with the heat equation. We will show how a Sand Tank Groundwater Model can be used to simulate groundwater flow through an aquifer with a no flow boundary condition.

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Designing A Convection-Cloud Chamber For Collision-Coalescence Using Large-Eddy Simulation With Bin Microphysics, Aaron Wang, Mikhail Ovchinnikov, Fan Yang, Silvio Schmalfuss, Raymond A. Shaw Jan 2024

Designing A Convection-Cloud Chamber For Collision-Coalescence Using Large-Eddy Simulation With Bin Microphysics, Aaron Wang, Mikhail Ovchinnikov, Fan Yang, Silvio Schmalfuss, Raymond A. Shaw

Michigan Tech Publications, Part 2

Collisional growth of cloud droplets is an essential yet uncertain process for drizzle and precipitation formation. To improve the quantitative understanding of this key component of cloud-aerosol-turbulence interactions, observational studies of collision-coalescence in a controlled laboratory environment are needed. In an existing convection-cloud chamber (the Pi Chamber), collisional growth is limited by low liquid water content and short droplet residence times. In this work, we use numerical simulations to explore various configurations of a convection-cloud chamber that may intensify collision-coalescence. We employ a large-eddy simulation (LES) model with a size-resolved (bin) cloud microphysics scheme to explore how cloud properties and …

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Fluid Flow, Mineralization And Deformation In An Oceanic Detachment Fault: Microtextural, Geochemical And Isotopic Evidence From Pyrite At 13°30′N On The Mid-Atlantic Ridge, Andrew J. Martin, John W. Jamieson, Sven Petersen, Mostafa Fayek, Javier Escartin Jan 2024

Fluid Flow, Mineralization And Deformation In An Oceanic Detachment Fault: Microtextural, Geochemical And Isotopic Evidence From Pyrite At 13°30′N On The Mid-Atlantic Ridge, Andrew J. Martin, John W. Jamieson, Sven Petersen, Mostafa Fayek, Javier Escartin

Geoscience Faculty Research

Hydrothermal fluids in ultramafic-hosted hydrothermal systems associated with oceanic detachment faults can be more oxidizing compared to mafic-hosted vent sites. These fluids form a mineral assemblage of pyrite, magnetite and hematite. At 13°30′N on the Mid-Atlantic Ridge, chlorite-quartz breccias recovered from an exposed fault scarp contain pyrite, with abundant magnetite and hematite, indicating that the redox of the fluids was variable. In primary micron-scale zonations in pyrite, Ni, Co, and Se have a decoupled relationship, recording fluctuations in the chemical composition and temperature of hydrothermal fluid as the grains grew. Secondary zonations that erase and overprint primary zonations are limited …

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Aftdc 2024 Session I English.- Decoding Complexity: Visualizing The Trans-Disciplinary Communication (Tdc) Logarithmic Spiral, Jasmin Cowin Jan 2024

Aftdc 2024 Session I English.- Decoding Complexity: Visualizing The Trans-Disciplinary Communication (Tdc) Logarithmic Spiral, Jasmin Cowin

Trans-Disciplinary Communication

No abstract provided.

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Aftdc 2024 Session Ii Español.- Open Science Framework (Osf) Como Herramienta Para La Colaboración Transdisciplinaria, Cristo Leon Jan 2024

Aftdc 2024 Session Ii Español.- Open Science Framework (Osf) Como Herramienta Para La Colaboración Transdisciplinaria, Cristo Leon

Trans-Disciplinary Communication

No abstract provided.

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Aftdc 2024 Open Discussion On The Association's Vision: An Opportunity For All Members To Share And Shape The Future Direction Of Aftdc, Cristo Leon Jan 2024

Aftdc 2024 Open Discussion On The Association's Vision: An Opportunity For All Members To Share And Shape The Future Direction Of Aftdc, Cristo Leon

Trans-Disciplinary Communication

No abstract provided.

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Aftdc 2024 Keynote.- The Significance And Vital Role Of Student Participation In Peer Review For Transdisciplinary Communication, Nagib Callaos Jan 2024

Aftdc 2024 Keynote.- The Significance And Vital Role Of Student Participation In Peer Review For Transdisciplinary Communication, Nagib Callaos

Trans-Disciplinary Communication

Join Dr. Nagib Callaos at the inaugural AFTDC meeting for a groundbreaking keynote on the transformative role of student participation in peer review for transdisciplinary communication. Delve into the intellectual, educational, and pragmatic benefits as Dr. Callaos explores the impact on personal and societal good. Discover how this practice enhances critical thinking, intellectual diversity, and adaptability in the face of rapid technological and societal changes. Learn about the significant role of educational systems in fostering intellectual diversification and skill development. The keynote will highlight the unique value of engaging students in peer review processes, especially in transdisciplinary settings, underlining its …

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Aftdc 2024 Welcome And Opening Remarks, Cristo Leon, James Lipuma Dr. Jan 2024

Aftdc 2024 Welcome And Opening Remarks, Cristo Leon, James Lipuma Dr.

Trans-Disciplinary Communication

Our primary focus is to discuss the effective establishment, nurturing, and expansion of chapters within the American Association for Trans-Disciplinary Communication (AFTDC).

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Fish Assemblage Structure In Great Lakes Coastal Wetlands Over Ten Years, Matthew S. Silverhart Jan 2024

Fish Assemblage Structure In Great Lakes Coastal Wetlands Over Ten Years, Matthew S. Silverhart

Masters Theses

Coastal wetlands in the Laurentian Great Lakes are important habitats for many fish species. The geographic scale of the watershed and the diversity of land uses in the region result in substantial environmental variation among coastal wetlands. During 2011-2020, annual surveys were conducted as part of the Great Lakes Coastal Wetland Monitoring Program (GLCWMP) to better understand the status and trends of coastal wetlands. Fish sampling consisted of fyke netting in monodominant vegetation zones. During this time, 1225 unique monodominant plant zones in coastal wetlands were sampled, resulting in 584,125 fishes captured that consisted of 113 different species. Yellow Perch …

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Integrating External Controls By Regression Calibration For Genome-Wide Association Study, Lirong Zhu, Shijia Yan, Xuewei Cao, Shuanglin Zhang, Qiuying Sha Jan 2024

Integrating External Controls By Regression Calibration For Genome-Wide Association Study, Lirong Zhu, Shijia Yan, Xuewei Cao, Shuanglin Zhang, Qiuying Sha

Michigan Tech Publications, Part 2

Genome-wide association studies (GWAS) have successfully revealed many disease-associated genetic variants. For a case-control study, the adequate power of an association test can be achieved with a large sample size, although genotyping large samples is expensive. A cost-effective strategy to boost power is to integrate external control samples with publicly available genotyped data. However, the naive integration of external controls may inflate the type I error rates if ignoring the systematic differences (batch effect) between studies, such as the differences in sequencing platforms, genotype-calling procedures, population stratification, and so forth. To account for the batch effect, we propose an approach …

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Piecing Together Performance: Collaborative, Participatory Research-Through-Design For Better Diversity In Games, Daniel L. Gardner, Louanne Boyd, Reginald T. Gardner Jan 2024

Piecing Together Performance: Collaborative, Participatory Research-Through-Design For Better Diversity In Games, Daniel L. Gardner, Louanne Boyd, Reginald T. Gardner

Engineering Faculty Articles and Research

Digital games are a multi-billion-dollar industry whose production and consumption extend globally. Representation in games is an increasingly important topic. As those who create and consume the medium grow ever more diverse, it is essential that player or user-experience research, usability, and any consideration of how people interface with their technology is exercised through inclusive and intersectional lenses. Previous research has identified how character configuration interfaces preface white-male defaults [39, 40, 67]. This study relies on 1-on-1 play-interviews where diverse participants attempt to create “themselves” in a series of games and on group design activities to explore how participants may …

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Innovative Cyanine-Based Fluorescent Dye For Targeted Mitochondrial Imaging And Its Utility In Whole-Brain Visualization, Xin Yan, Xinqian Chen, Zhiying Shan, Lanrong Bi Jan 2024

Innovative Cyanine-Based Fluorescent Dye For Targeted Mitochondrial Imaging And Its Utility In Whole-Brain Visualization, Xin Yan, Xinqian Chen, Zhiying Shan, Lanrong Bi

Michigan Tech Publications, Part 2

Conducting in vivo brain imaging can be a challenging task due to the complexity of brain tissue and the strict requirements for safe and effective imaging agents. However, a new fluorescent dye called Cy5-PEG2 has been developed that selectively accumulates in mitochondria, enabling the visualization of these essential organelles in various cell lines. This dye is versatile and can be used for the real-time monitoring of mitochondrial dynamics in living cells. Moreover, it can cross the blood-brain barrier, making it a promising tool for noninvasive in vivo brain imaging. Based on the assessment of glial cell responses in the hippocampus …

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