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Articles 26461 - 26490 of 302511

Full-Text Articles in Physical Sciences and Mathematics

Molecular Docking And Dynamics Simulation Studies To Predict Multiple Medicinal Plants’ Bioactive Compounds Interaction And Its Behavior On The Surface Of Denv-2 E Protein, Arief Hidayatullah, Wira Eka Putra, Muhaimin Rifa’I, Sustiprijatno Sustiprijatno, Diana Widiastuti, Muhammad Fikri Heikal, Hendra Susanto, Wa Ode Salma, Hilal Mulyadi Aug 2022

Molecular Docking And Dynamics Simulation Studies To Predict Multiple Medicinal Plants’ Bioactive Compounds Interaction And Its Behavior On The Surface Of Denv-2 E Protein, Arief Hidayatullah, Wira Eka Putra, Muhaimin Rifa’I, Sustiprijatno Sustiprijatno, Diana Widiastuti, Muhammad Fikri Heikal, Hendra Susanto, Wa Ode Salma, Hilal Mulyadi

Karbala International Journal of Modern Science

The envelope protein (E) is a fusion class II protein that is essential for DENV fusion. We use two active compounds derived from commonly used plants in Indonesia: galangin and kaempferide. We ran a docking and 1000 ps molecular dynamic analysis with normal physiological parameters. During the simulation, galangin and kaempferide binding sites fluctuated. But chloroquine has lesser ligand mobility, hence keeping contact with fusion loops, whereas both drugs lose contact with hydrophobic pockets. However, the two active compounds have a more stable ligand configuration. Less than 2 Å alterations were seen in the RMSF simulation of the protein E …

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Effects Of Spatially Heterogeneous Lakeside Development On Nearshore Biotic Communities In A Large, Deep, Oligotrophic Lake, Michael F. Meyer, Ted Ozersky, Kara H. Woo, Kirill Shchapov, Aaron W. E. Galloway, Julie B. Schram, Emma J. Rosi, Daniel D. Snow, Maxim A. Timofeyev, Dmitry Yu. Karnaukhov, Matthew R. Brousil, Stephanie E. Hampton Aug 2022

Effects Of Spatially Heterogeneous Lakeside Development On Nearshore Biotic Communities In A Large, Deep, Oligotrophic Lake, Michael F. Meyer, Ted Ozersky, Kara H. Woo, Kirill Shchapov, Aaron W. E. Galloway, Julie B. Schram, Emma J. Rosi, Daniel D. Snow, Maxim A. Timofeyev, Dmitry Yu. Karnaukhov, Matthew R. Brousil, Stephanie E. Hampton

School of Natural Resources: Faculty Publications

Sewage released from lakeside development can reshape ecological communities. Nearshore periphyton can rapidly assimilate sewage-associated nutrients, leading to increases of filamentous algal abundance, thus altering both food abundance and quality for grazers. In Lake Baikal, a large, ultra-oligotrophic, remote lake in Siberia, filamentous algal abundance has increased near lakeside developments, and localized sewage input is the suspected cause. These shifts are of particular interest in Lake Baikal, where endemic littoral biodiversity is high, lakeside settlements are mostly small, tourism is relatively high (~1.2 million visitors annually), and settlements are separated by large tracts of undisturbed shoreline, enabling investigation of heterogeneity …

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Vertex-Magic Graphs, Karissa Massud Aug 2022

Vertex-Magic Graphs, Karissa Massud

Honors Program Theses and Projects

In this paper, we will study magic labelings. Magic labelings were first introduced by Sedláček in 1963 [3]. At this time, the labels on the graph were only assigned to the edges. In 1970, Kotzig and Rosa defined what are now known as edge-magic total labelings, where both the vertices and the edges of the graph are labeled. Following this in 1999, MacDougall, Miller, Slamin, and Wallis introduced the idea of vertex-magic total labelings. There are many different types of magic labelings. In this paper will focus on vertex-magictotal labelings.

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Meta-Analysis Reveals Both The Promises And The Challenges Of Clinical Metabolomics, Heidi E. Roth, Robert Powers Aug 2022

Meta-Analysis Reveals Both The Promises And The Challenges Of Clinical Metabolomics, Heidi E. Roth, Robert Powers

Chemistry Department: Faculty Publications

Clinical metabolomics is a rapidly expanding field focused on identifying molecular biomarkers to aid in the efficient diagnosis and treatment of human diseases. Variations in study design, metabolomics methodologies, and investigator protocols raise serious concerns about the accuracy and reproducibility of these potential biomarkers. The explosive growth of the field has led to the recent availability of numerous replicate clinical studies, which permits an evaluation of the consistency of biomarkers identified across multiple metabolomics projects. Pancreatic ductal adenocarcinoma (PDAC) is the third-leading cause of cancer-related death and has the lowest five-year survival rate primarily due to the lack of an …

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A Graph Method For Interpretation Of Magnetic Anomalies Over 2d Dikes And Vertical Faults, İbrahim Kara, Oya Tarhan Bal, Anisya B.Tekkeli̇ Aug 2022

A Graph Method For Interpretation Of Magnetic Anomalies Over 2d Dikes And Vertical Faults, İbrahim Kara, Oya Tarhan Bal, Anisya B.Tekkeli̇

Bulletin of the Mineral Research and Exploration

Simple geometric assumptions for dikes and faults are often used for interpreting the parameters of these structures from magnetic anomalies. The magnetic anomaly of a 2D dike or a vertical fault consists of two components; one with even and the other with odd symmetries. The function resulting from the ratio of the even and odd components is independent from the amplitude coefficient. The abscissa of the half-maximum of the even component and the maximum of the odd component of a dike or a vertical fault is related to its depth and its half-width. Incorporating this relation into the corresponding equations …

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The Foundations Of Mathematics: Axiomatic Systems And Incredible Infinities, Catherine Ferris Aug 2022

The Foundations Of Mathematics: Axiomatic Systems And Incredible Infinities, Catherine Ferris

Honors Program Theses and Projects

Often, people who study mathematics learn theorems to prove results in and about the vast array of branches of mathematics (Algebra, Analysis, Topology, Geometry, Combinatorics, etc.). This helps them move forward in their understanding; but few ever question the basis for these theorems or whether those foundations are sucient or even secure. Theorems come from our foundations of mathematics, Axioms, Logic and Set Theory. In the early20th century, mathematicians set out to formalize the methods, operations and techniques people were assuming. In other words, they were formulating axioms. The most common axiomatic system is known as the Zermelo-Fraenkel axioms with …

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The Role Of Surprise In Guessing Games, Justin Carpender Aug 2022

The Role Of Surprise In Guessing Games, Justin Carpender

Honors Program Theses and Projects

In this thesis we will study the connection between game structure, surprise, and guessing strategies for these first two versions of a word guessing game. Our analysis will have three levels: one, a basic understanding of language and letter probabilities and the creation of programs that seek to use the structure of a game to efficiently guess words; two, an introduction of mathematical background and Information Theory; three, an analysis of the games and their corresponding guesses via a creative use of the key ideas of Information Theory, particularly, the concepts of surprise and entropy.

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Deep Space And The Quantum Mechanical Case: A Study Of Stars To The First Bsu Direct Measurement Of A Singular Photon, Darius Desnoes Aug 2022

Deep Space And The Quantum Mechanical Case: A Study Of Stars To The First Bsu Direct Measurement Of A Singular Photon, Darius Desnoes

Honors Program Theses and Projects

While it is known that physics can be split into several different fields, it may be foreign to see how different fields of physics operate hand in hand with one another to solve complex problems. For instance, Maxwell’s equations involving E&M for the propagation of electro-magnetic waves can be used to understand light-based interferometry for astrophysics, which directly led to the creation of intensity-based interferometry. Eventually, the measurements and equations made by intensity-based interferometry would produce groundbreaking strides in quantum mechanics through the direct measurement of singular particles. An in-depth analysis of each of these connections and how they involved …

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Vertex-Magic Total Labeling On G-Sun Graphs, Melissa Mejia Aug 2022

Vertex-Magic Total Labeling On G-Sun Graphs, Melissa Mejia

Honors Program Theses and Projects

Graph labeling is an immense area of research in mathematics, specifically graph theory. There are many types of graph labelings such as harmonious, magic, and lucky labelings. This paper will focus on magic labelings. Graph theorists are particularly interested in magic labelings because of a simple problem regarding tree graphs introduced in the 1990’s. The problem is still unsolved after almost thirty years. Researchers have studied magic labelings on other graphs in addition to tree graphs. In this paper we will consider vertex-magic labelings on G-sun graphs. We will give vertex-magic total labelings for ladder sun graphs and complete bipartite …

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Reverberation Mapping Of Markarian 421 Using V,R, I, And Ha Filters, Alex Whitman Aug 2022

Reverberation Mapping Of Markarian 421 Using V,R, I, And Ha Filters, Alex Whitman

Honors Program Theses and Projects

Active Galactic Nuclei (AGN) at their most basic level are supermassive blackholes that emit light. While that sounds paradoxical, it speaks volumes to how little we know about these extraordinary objects. One technique that can be used, and was used here to better understand these objects is reverberation mapping. We employed this method on the AGN Markarian 421 (Mrk 421) at Bridgewater State University (BSU). Mrk 421 was chosen because it is the brightest known AGN, averaging 12.7 magnitudes, and the observational abilities of BSU are best suited for objects brighter than 18 magnitudes in optical wavelengths. We observed Mrk …

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Collateral Damage: Anticoagulant Rodenticides Pose Threats To California Condors, Garth Herring, Collin A. Eagles-Smith, Rachel Wolstenholme, Alacia Welch, Chris West, Barnett A. Rattner Aug 2022

Collateral Damage: Anticoagulant Rodenticides Pose Threats To California Condors, Garth Herring, Collin A. Eagles-Smith, Rachel Wolstenholme, Alacia Welch, Chris West, Barnett A. Rattner

United States Geological Survey: Staff Publications

Anticoagulant rodenticides (ARs) are widespread environmental contaminants that pose risks to scavenging birds because they routinely occur within their prey and can cause secondary poisoning. However, little is known about AR exposure in one of the rarest avian scavengers in the world, the California condor (Gymnogyps californianus). We assessed AR exposure in California condors and surrogate turkey vultures (Cathartes aura) to gauge potential hazard to a proposed future condor flock by determining how application rate and environmental factors influence exposure. Additionally, we examined whether ARs might be correlated with prolonged blood clotting time and potential mortality …

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Data Engineering Techniques And Designs With Music Generating Neural Networks, Noah Solomon Aug 2022

Data Engineering Techniques And Designs With Music Generating Neural Networks, Noah Solomon

Honors Program Theses and Projects

The generation of music artificially is an interesting concept to many and has received a lot of attention in recent years. The advancement of neural networks has allowed for the creation of models that can seemingly generate music creatively to mimic a specific genre or composer. This project delved deep into the many ways to construct music generating neural networks and compared different model architectures and data engineering techniques. Three main types of models were implemented and the resulting generated music was evaluated with respect to the melody, note agreeableness, and rhythm. These models used the Bach Chorales corpus as …

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Using Optical Tweezersto Probe Dna Polymerase Kappa’S Binding Mechanism To Dna, Joshua Watts Aug 2022

Using Optical Tweezersto Probe Dna Polymerase Kappa’S Binding Mechanism To Dna, Joshua Watts

Honors Program Theses and Projects

The integrity of our DNA is constantly under threat from many internal and external factors. If the cell cannot properly protect the integrity of DNA, errors (lesions) in DNA may form which can lead to cancer. Most of these lesions serve as a roadblock to the protein, DNA polymerase (Pol), that replicates the DNA during cell division. The mechanism that is employed to read through these errors is called translesion DNA synthesis (TLS). During this process, a special class of DNA polymerases known as TLS DNA Pols that can tolerate and bypass the lesions in DNA are employed by the …

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Zno Nano-Swirlings For Azo Dye Ar183 Photocatalytic Degradation And Antimycotic Activity, Khalid Umar, Manar Fawzi Bani Mfarrej, Qazi Inamur Rahman, Mohammad Zuhaib, Amir Khan, Qamar Zia, Saeed Banawas, Hera Nadeem, Mohd. Farhan Khan, Faheem Ahmad Aug 2022

Zno Nano-Swirlings For Azo Dye Ar183 Photocatalytic Degradation And Antimycotic Activity, Khalid Umar, Manar Fawzi Bani Mfarrej, Qazi Inamur Rahman, Mohammad Zuhaib, Amir Khan, Qamar Zia, Saeed Banawas, Hera Nadeem, Mohd. Farhan Khan, Faheem Ahmad

All Works

The sol-gel technique was used to fabricate ZnO Nano-swirlings (ZNsw) at a predetermined agitation rate (of >> 1900 rpm), with around 21.94 gm of zinc acetate dihydrate and 0.2 g cetyltrimethylammoniumbromide (CTAB) and a cationic surfactant (drop-wise). The impact of the predetermined agitation condition on the molecular size and morphology of ZNsw is examined, and the outcomes are dissected by useful characterization tools and techniques viz. XRD, SEM embedded with EDS, TEM, FT-IR and UV–visible. The SEM and TEM results suggest that the product formed into a big cluster of adequate ZNsw, containing a significant quantity of folded long thread-lengths. Each …

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Experimental Infection Of Brazilian Free-Tailed Bats (Tadarida Brasiliensis) With Two Strains Of Sars-Cov-2, Angela M. Bosco-Lauth, Stephanie M. Porter, Karen A. Fox, Mary E. Wood, Daniel Neubaum, Marissa Quilici Aug 2022

Experimental Infection Of Brazilian Free-Tailed Bats (Tadarida Brasiliensis) With Two Strains Of Sars-Cov-2, Angela M. Bosco-Lauth, Stephanie M. Porter, Karen A. Fox, Mary E. Wood, Daniel Neubaum, Marissa Quilici

United States Department of Agriculture Wildlife Services: Staff Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is presumed to have originated from wildlife and shares homology with other bat coronaviruses. Determining the susceptibility of North American bat species to SARS-CoV-2 is of utmost importance for making decisions regarding wildlife management, public health, and conservation. In this study, Brazilian free-tailed bats (Tadarida brasiliensis) were experimentally infected with two strains of SARS-CoV-2 (parental WA01 and Delta variant), evaluated for clinical disease, sampled for viral shedding and antibody production, and analyzed for pathology. None of the bats (n = 18) developed clinical disease associated with infection, shed infectious virus, or …

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Microplastics In The Marine Environment And Deep-Sea Sediment Contamination: A Review, Elizabeth Sangiolo Aug 2022

Microplastics In The Marine Environment And Deep-Sea Sediment Contamination: A Review, Elizabeth Sangiolo

Honors Program Theses and Projects

This review discusses what microplastics are and how they are continuously impacting the marine environment, and ultimately, human life. Plastic has been the number one used material for decades for industrial and recreational purposes. Its cost effectiveness, durability, and lightness are what manufacturers and consumers desire most, making plastic the most abundant pollutant in the world. Understanding how plastic pollution is broken down into microplastics and how these fragmented pieces of waste are classified can help researchers identify ways to prevent the additional input of microplastics in the marine environment. These microscopic particles of debris have been sampled from deep-sea …

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Effect Of Ligands And Their Removal On The Au Nanoparticle-Catalyzed Reduction Of 4-Nitrophenol, Nicholas Langer, Ofer Kedem Aug 2022

Effect Of Ligands And Their Removal On The Au Nanoparticle-Catalyzed Reduction Of 4-Nitrophenol, Nicholas Langer, Ofer Kedem

Chemistry Faculty Research and Publications

The catalytic activity of gold nanoparticles (Au NPs) is strongly affected by the organic ligands coating them, which afford colloidal stability and are most commonly attached during the synthesis of the Au NPs. However, different ligands also produce Au NPs of different sizes and morphologies, complicating the study of the impact of the ligands themselves. Alternatively, postsynthetic ligand exchange risks incomplete exchanges and a mixed ligand shell, as well as colloidal instability. Here, Au NPs are immobilized on glass supports to afford truly ligand-free, solvent-stable Au nanoislands (NIs). The catalytic activity of Au NIs, uncoated and coated with a variety …

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Statistical Analysis Methods Applied To Early Outpatient Covid-19 Treatment Case Series Data, Eleftherios Gkioulekas, Peter A. Mccullough, Vladimir Zelenko Aug 2022

Statistical Analysis Methods Applied To Early Outpatient Covid-19 Treatment Case Series Data, Eleftherios Gkioulekas, Peter A. Mccullough, Vladimir Zelenko

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

When confronted with a public health emergency, significant innovative treatment protocols can sometimes be discovered by medical doctors at the front lines based on repurposed medications. We propose a statistical framework for analyzing the case series of patients treated with such new protocols, that enables a comparison with our prior knowledge of expected outcomes, in the absence of treatment. The goal of the proposed methodology is not to provide a precise measurement of treatment efficacy, but to establish the existence of treatment efficacy, in order to facilitate the binary decision of whether the treatment protocol should be adopted on an …

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Spectral Analysis Of Multiscale Cultural Traits On Twitter, Chandler Squires, Nikhil Kunapuli, Yaneer Bar-Yam, Alfredo Morales Aug 2022

Spectral Analysis Of Multiscale Cultural Traits On Twitter, Chandler Squires, Nikhil Kunapuli, Yaneer Bar-Yam, Alfredo Morales

Northeast Journal of Complex Systems (NEJCS)

Understanding and mapping the emergence and boundaries of cultural areas is a challenge for social sciences. In this paper, we present a method for analyzing the cultural composition of regions via Twitter hashtags. Cultures can be described as distinct combination of traits which we capture via principal component analysis (PCA). We investigate the top 8 PCA components of an area including France, Spain, and Portugal, in terms of the geographic distribution of their hashtag composition. We also discuss relationships between components and the insights those relationships can provide into the structure of a cultural space. Finally, we compare the spatial …

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An Analysis Of Weighted Least Squares Monte Carlo, Xiaotian Zhu Aug 2022

An Analysis Of Weighted Least Squares Monte Carlo, Xiaotian Zhu

Electronic Thesis and Dissertation Repository

Since Longstaff and Schwartz [2001] brought the amazing Regression-based Monte Carlo (LSMC) method in pricing American options, it has received heated discussion. Based on the research done by Fabozzi et al. [2017] that applies the heteroscedasticity correction method to LSMC, we further extend the study by introducing the methods from Park [1966] and Harvey [1976]. Our work shows that for a single stock American Call option modelled by GBM with two exercise opportunities, WLSMC or IRLSMC provides better estimates in continuation value than LSMC. However, they do not lead to better exercise decisions and hence have little to no effect …

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Mgrre_Thinsections_Mgrre-108_5, Mgrre Aug 2022

Mgrre_Thinsections_Mgrre-108_5, Mgrre

Thin Sections

No abstract provided.

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Mgrre_Thinsections_Mgrre-108_3, Mgrre Aug 2022

Mgrre_Thinsections_Mgrre-108_3, Mgrre

Thin Sections

No abstract provided.

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Mgrre_Thinsections_Mgrre-108_7, Mgrre Aug 2022

Mgrre_Thinsections_Mgrre-108_7, Mgrre

Thin Sections

No abstract provided.

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Mgrre_Thinsections_Mgrre-108_9, Mgrre Aug 2022

Mgrre_Thinsections_Mgrre-108_9, Mgrre

Thin Sections

No abstract provided.

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Mgrre_Thinsections_Mgrre-108_10, Mgrre Aug 2022

Mgrre_Thinsections_Mgrre-108_10, Mgrre

Thin Sections

No abstract provided.

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Mgrre_Thinsections_Mgrre-108_14, Mgrre Aug 2022

Mgrre_Thinsections_Mgrre-108_14, Mgrre

Thin Sections

No abstract provided.

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Mgrre_Thinsections_Mgrre-108_16, Mgrre Aug 2022

Mgrre_Thinsections_Mgrre-108_16, Mgrre

Thin Sections

No abstract provided.

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Mgrre_Thinsections_Mgrre-108_18, Mgrre Aug 2022

Mgrre_Thinsections_Mgrre-108_18, Mgrre

Thin Sections

No abstract provided.

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Mgrre_Thinsections_Mgrre-108_1, Mgrre Aug 2022

Mgrre_Thinsections_Mgrre-108_1, Mgrre

Thin Sections

No abstract provided.

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Mgrre_Thinsections_Mgrre-108_2, Mgrre Aug 2022

Mgrre_Thinsections_Mgrre-108_2, Mgrre

Thin Sections

No abstract provided.

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