Physical Sciences and Mathematics Commons^™

Clean & Fast Amide Couplings In Water, Nicklas Buckbinder, Sudripet Sharma, Sachin Handa

Undergraduate Research Events

EDC

(1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide) is a carbodiimide that is well known reagent for the amide coupling reactions between an amine and carboxylic acid in the presence of a base. It is the commonly used coupling agent in industries because it produces a water-soluble urea byproduct, which can be easily removed by an aqueous work-up. However, our methodology, the desired amide product precipitates out of the reaction mixture, and no additional work-up is required.3 Using aqueous micelles of PS-750-M as a solvent dramatically increases the rate of reaction.2 The filtrate recovered can be recycled to perform several coupling runs after post-reaction manipulation.

Modification Of Chm20 Lab: Synthesis Of Aspirin, Nicole Diaz, Amy Musselman Prof.

KU Inspires! Undergraduate Research Day

No abstract provided.

Environmentally Clean Access To Antarctic Subglacial Aquatic Environments, Alexander B. Michaud, Trista (Vick-Majors, Amanda M. Achberger, Mark L. Skidmore, Brent C. Christner, Martyn Tranter, John C. Priscu

Faculty Publications

Subglacial Antarctic aquatic environments are important targets for scientific exploration due to the unique ecosystems they support and their sediments containing palaeoenvironmental records. Directly accessing these environments while preventing forward contamination and demonstrating that it has not been introduced is logistically challenging. The Whillans Ice Stream Subglacial Access Research Drilling (WISSARD) project designed, tested and implemented a microbiologically and chemically clean method of hot-water drilling that was subsequently used to access subglacial aquatic environments. We report microbiological and biogeochemical data collected from the drilling system and underlying water columns during sub-ice explorations beneath the McMurdo and Ross ice shelves and …

Tidal And Storm Impacts On Hydrodynamics And Sediment Dynamics In An Energetic Ebb Tidal Delta, Kehui Xu, P. Ansley Wren, Yanxia Ma

Faculty Publications

Bottom-mounted instrumentation was deployed at two sites on a large sandy shoal of an ebb tidal delta offshore of the Port Royal Sound of South Carolina of USA to collect hydrodynamics and sediment dynamics data. One site ("borrow site") was 2 km offshore in a dredge pit for nearby beach nourishment and the other site ("reference site") was 10 km offshore. In situ time-series data were collected during two periods after the dredging: 15 March-12 June (spring) and 18 August-18 November (fall) of 2012. Data at the reference site indicated active migrating bedforms from centimeters to decimeters tall, and sediment …

The Dynamic Trophic Niche Of An Island Bird Of Prey, Ulises Balza, Nicolas A. Lois, Michael J. Polito, Klemens Puetz, Amira Saalom, Andrea Raya Rey

Faculty Publications

Optimal foraging theory predicts an inverse relationship between the availability of preferred prey and niche width in animals. Moreover, when individuals within a population have identical prey preferences and preferred prey is scarce, a nested pattern of trophic niche is expected if opportunistic and selective individuals can be identified. Here, we examined intraspecific variation in the trophic niche of a resident population of striated caracara (Phalcoboenus australis) on Isla de los Estados (Staten Island), Argentina, using pellet and stable isotope analyses. While this raptor specializes on seabird prey, we assessed this population's potential to forage on terrestrial prey, especially invasive …

Fish Assemblages Associated With Artificial Reefs Assessed Using Multiple Gear Types In The Northwest Gulf Of Mexico, Jeffrey D. Plumlee, Kaylan M. Dance, Michael A. Dance, Hay R. Rooker, Thomas C. Tinhan, J. Brooke Shipley, R. J. David Wells

Faculty Publications

Quantitative surveys of fishes associated with artificial reefs in the northwest Gulf of Mexico were conducted over a 4-yr period (2014-2017). Artificial reefs surveyed were comprised of three types: concrete structures, rig jackets, and decommissioned ships. All reefs were surveyed using vertical long line ( VLL), fish traps, and Adaptive Resolution Imaging Sonar (ARIS 1800). Mean fish abundance did not significantly differ using VLL [1.7 ind set(-1) (SD 2.2)] among the three reef types. However, relative abundance among all fishes collected was significantly highest on rig reefs using traps [6.2 ind soak(-1) (SD 3.8)], while results from sonar surveys indicated …

All-Atomic Molecular Dynamic Studies Of Human And Drosophila Cdk8: Insights Into Their Kinase Domains, The Lxxll Motifs, And Drug Binding Site, Wu Xu, Xiao-Jun Xie, Ali K. Faust, Mengmeng Liu, Xiao Li, Feng Chen, Ashlin A. Naquin, Avery C. Walton, Peter W. Kishbaugh, Jun-Yuan Ji

Faculty Publications

Cyclin-dependent kinase 8 (CDK8) and its regulatory partner Cyclin C (CycC) play conserved roles in modulating RNA polymerase II (Pol II)-dependent gene expression. To understand the structure and function relations of CDK8, we analyzed the structures of human and Drosophila CDK8 proteins using molecular dynamics simulations, combined with functional analyses in Drosophila. Specifically, we evaluated the structural differences between hCDK8 and dCDK8 to predict the effects of the LXXLL motif mutation (AQKAA), the P154L mutations, and drug binding on local structures of the CDK8 proteins. First, we have observed that both the LXXLL motif and the kinase activity of CDK8 …

Nest Moisture Content Affects Loggerhead Hatchling Size And Neonate Development, Kelly M. Detmer

Scientific Communication News

No abstract provided.

Issues And Proposed Solutions To Team Based Assessment In University Physics Labs, Manqoba Q. Hlatshwayo

STEM Instructional Graduate Teaching Assistant Posters

Many education experts considers peer-to-peer education as the most effective way for students to learn (Peersdom, 2014). Western Michigan University (WMU) physics laboratories embraces this philosophy and has designed the assessment to be based on the team report. The assumption is that every team member contributed (not necessarily equally) to the work submitted by the team hence every team member should receive the same grade. This is a ubiquitous assessment philosophy in education, and some forms of additional individual assessment in team projects are strongly discouraged (David Boud et al, 1999).

There is no doubt on the effectiveness of peer-to-peer …

Abstract Algebra: Theory And Applications, Thomas W. Judson

eBooks

Tom Judson's Abstract Algebra: Theory and Applications is an open source textbook designed to teach the principles and theory of abstract algebra to college juniors and seniors in a rigorous manner. Its strengths include a wide range of exercises, both computational and theoretical, plus many nontrivial applications. Rob Beezer has contributed complementary material using the open source system, Sage.

An HTML version on the PreText platform is available here.

The first half of the book presents group theory, through the Sylow theorems, with enough material for a semester-long course. The second-half is suitable for a second semester and …

College Of Natural Sciences Newsletter, October 2020, College Of Natural Sciences

College of Natural Sciences Newsletters and Reports

Volume 1. Issue 9

Content:

Dean’s Update P.1
Awards & Recognition P.2
Student Club Spotlight P.3
Open PRAIRIE | Research Overview P.4
Interest in Science | Updates P.5
Where’s Wil? P.6 Art
Competition Announcement P.7

Data Analytics Beyond Traditional Probabilistic Approach To Uncertainty, Vladik Kreinovich

Departmental Technical Reports (CS)

Data for processing mostly comes from measurements, and measurements are never absolutely accurate: there is always the "measurement error" -- the difference between the measurement result and the actual (unknown) value of the measured quantity. In many applications, it is important to find out how these measurement errors affect the accuracy of the result of data processing. Traditional data processing techniques implicitly assume that we know the probability distributions. In many practical situations, however, we only have partial information about these distributions. In some cases, all we know is the upper bound on the absolute value of the measurement error. …

How To Explain The Relation Between Different Empirical Covid-19 Self-Isolation Periods, Christian Servin, Olga Kosheleva, Vladik Kreinovich

Departmental Technical Reports (CS)

Empirical data implies that, to avoid infecting others, an asymptomatic career of Covid-19 should self-isolate for a period of 10 days, a patient who experiences symptoms for 20 days, and a person who was in contact with a Covid-19 patient should self-isolate for 14 days. In this paper, we use Laplace's Principle of Insufficient Reason to provide a simple explanation for the relation between these three self-isolation periods.

What If We Use Almost-Linear Functions Instead Of Linear Ones As A First Approximation In Interval Computations, Martine Ceberio, Olga Kosheleva, Vladik Kreinovich

Departmental Technical Reports (CS)

In many practical situations, the only information that we have about measurement errors is the upper bound on their absolute values. In such situations, the only information that we have after the measurement about the actual (unknown) value of the corresponding quantity is that this value belongs to the corresponding interval: e.g., if the measurement result is 1.0, and the upper bound is 0.1, then this interval is [1.0−0.1,1.0+0.1] = [0.9,1.1]. An important practical question is what is the resulting interval uncertainty of indirect measurements, i.e., in other words, how interval uncertainty propagates through data processing. There exist feasible algorithms …

How To Describe Measurement Errors: A Natural Generalization Of The Central Limit Theorem Beyond Normal (And Other Infinitely Divisible) Distributions, Julio Urenda, Olga Kosheleva, Vladik Kreinovich

Departmental Technical Reports (CS)

When precise measurement instruments are designed, designers try their best to decrease the effect of the main factors leading to measurement errors. As a result of this decrease, the remaining measurement error is the joint result of a large number of relatively small independent error components. According to the Central Limit Theorem, under reasonable conditions, when the number of components increases, the resulting distribution tends to Gaussian (normal). Thus, in practice, when the number of components is large, the distribution is close to normal -- and normal distributions are indeed ubiquitous in measurements. However, in some practical situations, the distribution …

Why Significant Wave Height And Rogue Waves Are So Defined: A Possible Explanation, Laxman Bokati, Olga Kosheleva, Vladik Kreinovich

Departmental Technical Reports (CS)

Data analysis has shown that if we want to describe the wave pattern by a single characteristic, the best characteristic is the average height of the highest one third of the waves; this characteristic is called significant wave height. Once we know the value of this characteristic, a natural next question is: what is the highest wave that we should normally observe -- so that waves higher than this amount would be rare ("rogue"). Empirically, it has been shown that rogue waves are best defined as the ones which are at least twice higher than the significant wave height. In …

White- And Black-Box Computing And Measurements Under Limited Resources: Cloud, High Performance, And Quantum Computing, And Two Case Studies -- Robotic Boat And Hierarchical Covid Testing, Vladik Kreinovich, Martine Ceberio, Olga Kosheleva

Departmental Technical Reports (CS)

In many practical problems, it is important to take into account that our computational and measuring resources are limited. In this paper, we overview main resource limitations for different types of computers, and we provide two case studies explaining how to best take this resource limitation into account.

Analyzing Adverse Events From Publicly Available Web Sources, Alexander Salamun

Master's Theses (2009 -)

Data mining for drug-reaction associations is a major topic in the pharmaceutical industry. Historically the focus has been on using privately owned and maintained datasets consisting of information that has been transformed via the FDA Adverse Event Reporting System (FAERS) and privatized reporting systems that house the data from clinical trials. Our focus will be on building a pipeline that demonstrates an open source solution for building a drug’s safety profile from data collection through signal detection. In contrast this pipeline primarily uses the openFDA and social media data available through Reddit with all analysis being done in the R …

Towards Developing A Mobile-Based Care For Children With Asd Using Remote Experience Sampling Method (Mcare), Dipranjan Das

Master's Theses (2009 -)

Autism Spectrum Disorder (ASD) is the most prevalent among all of the neurodevelopmental disorders, which have increased 20-30 times in the last 50 years. A child with ASD requires regular monitoring, care, and support. But, the existing social-cultural-financial constraints and the scarcity of mental health care practitioners have deprived the families raising children with ASD in low-and middle-income countries (LMICs) like Bangladesh. However, the recent overwhelming adoption (~80%) of mobile phones has created an opportunity to improve the existing practice of care using affordable mobile applications. mCARE, a mobile-based care system, has been developed to reduce the gap between families …

Σ-Ary, Minnesota State University Moorhead, Mathematics Department

Math Department Newsletters

No abstract provided.

Geologic Map Of The Structural Margin Of Northeastern North America, Daniel Melnick

Earth & Space Sciences Student Work

No abstract provided.

Pharmacologic Ire1/Xbp1s Activation Confers Targeted Er Proteostasis Reprogramming, J. M. D. Grandjean, A. Madhavan, L. Cech, B. O. Seguinot, R. J. Paxman, E. Smith, L. Scampavia, E. T. Powers, Christina B. Cooley, L. Plate, T. P. Spicer, J. W. Kelly, R. L. Wiseman

Chemistry Faculty Research

Activation of the IRE1/XBP1s signaling arm of the unfolded protein response (UPR) is a promising strategy to correct defects in endoplasmic reticulum (ER) proteostasis implicated in diverse diseases. However, no pharmacologic activators of this pathway identified to date are suitable for ER proteostasis remodeling through selective activation of IRE1/XBP1s signaling. Here, we use high-throughput screening to identify non-toxic compounds that induce ER proteostasis remodeling through IRE1/XBP1s activation. We employ transcriptional profiling to stringently confirm that our prioritized compounds selectively activate IRE1/XBP1s signaling without activating other cellular stress-responsive signaling pathways. Furthermore, we demonstrate that our compounds improve ER proteostasis of destabilized …

Trail Impact Monitoring In Forest Park, James Mitchell

Environmental Science and Management Professional Master's Project Reports

Forest Park is an appropriately named 5,200 acre natural area located in northwest Portland, Oregon. A recent study estimated park usage near half a million annual visits and found "trails" to be the park’s most highly valued feature. Unfortunately, many trails were not designed for such traffic as evidenced by slipping hazards, erosion and other ecological impacts. In response to these observations, I partnered with Portland Parks & Recreation to conduct an objective trail impact assessment prescribed by the Forest Park Natural Resource Management Plan. I modified methods from past studies to expand on a recently completed trail condition class …

Santa Clara Magazine, Volume 61 Number 3, Fall 2020 [Print Issue V.61:2], Santa Clara University

Santa Clara Magazine

16 - THE GIFT Is sacrifice, given willingly and with love, what makes us human? Leslie Griffy.

20 - NOT A MOMENT, BUT A MOVEMENT From protests in Benson in 1969 to a multi-decade movement called Unity, students of color have consistently pushed SCU to progress. Matt Morgan.

28 - ON BEING BETTER Discover the ways we can better support each other, particularly as white people seek to become allies to people of color. Lauren Loftus.

32 - THE SACRIFICIAL TWEET Social media missteps are costly, perhaps now more than ever. Just what are we willing to give up to …

Pattern Of Health Behavior And Its Association With Self-Rated Health: Evidence From The 2018 Behavioral Risk Factor Surveillance System In The United States, Linh Nguyen, Mamunur Rashid, M Mazharul Islam

Annual Student Research Poster Session

Physical inactivity, tobacco use, and alcohol consumption are linked with increased morbidity and mortality. To improve public health services, we need to keep policymakers updated with health-related issues. Yet, there are limited numbers of recent research on the combination of those lifestyle behaviors as the determinants of self-rated health (SRH) in the US. Therefore, this study (1) examines the pattern of physical activities, smoking, alcohol consumption, and SRH, and (2) investigates the association between the behaviors and SRH status among US citizens. We extracted data from the latest state-based survey of the 2018 Behavioral Risk Factor Surveillance System (BRFSS), which …

Improving Lab Experience For Students In Phys2080, Khushi Bhatt

STEM Instructional Graduate Teaching Assistant Posters

University Physics II (PHYS 2080) deals with providing hands-on experience with the experiments of electricity and magnetism. It aids students to develop computational thinking in physics through analysis of experimental and theoretical data using python programming language.

In Fall-2019, I taught the newly designed PHYS2080 class for the first time as per the requirements. During Spring-2020, I implemented some subtle changes using the skills that I gained through various teaching training. These changes are described in Methodology section. Data clearly shows improvement that was observed without lowering the expectations or changing the curriculum of the class.

Secure Authentication And Privacy-Preserving Techniques In Vehicular Ad-Hoc Networks (Vanets), Dakshnamoorthy Manivannan, Shafika Showkat Moni, Sherali Zeadally

Computer Science Faculty Publications

In the last decade, there has been growing interest in Vehicular Ad Hoc NETworks (VANETs). Today car manufacturers have already started to equip vehicles with sophisticated sensors that can provide many assistive features such as front collision avoidance, automatic lane tracking, partial autonomous driving, suggestive lane changing, and so on. Such technological advancements are enabling the adoption of VANETs not only to provide safer and more comfortable driving experience but also provide many other useful services to the driver as well as passengers of a vehicle. However, privacy, authentication and secure message dissemination are some of the main issues that …

Quasilinearization Applied To Boundary Value Problems At Resonance For Riemann-Liouville Fractional Differential Equations, Paul W. Eloe, Jaganmohan Jonnalagadda

Mathematics Faculty Publications

The quasilinearization method is applied to a boundary value problem at resonance for a Riemann-Liouville fractional differential equation. Under suitable hypotheses, the method of upper and lower solutions is employed to establish uniqueness of solutions. A shift method, coupled with the method of upper and lower solutions, is applied to establish existence of solutions. The quasilinearization algorithm is then applied to obtain sequences of lower and upper solutions that converge monotonically and quadratically to the unique solution of the boundary value problem at resonance.

The Coastal Monitor Winter/Spring 2020 (Volume 6, No 2), John Tanacredi Ph.D.

The Coastal Monitor

It is a distinct pleasure to welcome our new President, Dr. James Lentini, who epitomizes the STEAM connection between Art and Science at Molloy College. Dr. Lentini has been a leader in higher education for more than 30 years and has had stellar academic training in the arts which include his passion for music. From composer, to classical guitarist, to music technology on an international level, receiving countless awards, honors, and praise from the most prestigious entities in the Arts. His transition to Molloy College was at the peak of the COVID-19 pandemic and his leadership, under these most difficult …

Direct Confirmation Of The Radial-Velocity Planet Β Pictoris C, M. Nowak, S. Lacour, A. M. Lagrange, P. Rubini, J. Wang, T. Stolker, R. Abuter, A. Amorim, R. Asensio-Torres, M. Bauböck, M. Benisty, J. P. Berger, H. Beust, S. Blunt, A. Boccaletti, M. Bonnefoy, H. Bonnet, W. Brandner, F. Cantalloube, B. Charnay, E. Choquet, V. Christiaens, Y. Clénet, V. Coudé Du Foresto, A. Cridland, P. T. De Zeeuw, R. Dembet, J. Dexter, A. Drescher, G. Duvert, A. Eckart, F. Eisenhauer, Kimberly Ward-Duong, Et Al

Astronomy: Faculty Publications

Context. Methods used to detect giant exoplanets can be broadly divided into two categories: indirect and direct. Indirect methods are more sensitive to planets with a small orbital period, whereas direct detection is more sensitive to planets orbiting at a large distance from their host star. This dichotomy makes it difficult to combine the two techniques on a single target at once. Aims. Simultaneous measurements made by direct and indirect techniques offer the possibility of determining the mass and luminosity of planets and a method of testing formation models. Here, we aim to show how long-baseline interferometric observations guided by …